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Select item 21988281.

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death

Andre Fortin, Sean P. Cregan, Jason G. MacLaurin, Neena Kushwaha, Emma S. Hickman, Charlie S. Thompson, Antoine Hakim, Paul R. Albert, Francesco Cecconi, Kristian Helin, David S. Park, Ruth S. Slack

J Cell Biol. 2001 Oct 15; 155(2): 207–216. doi: 10.1083/jcb.200105137

PMCID:: PMC2198828

Article PDF–300K

Select item 5576622.

Analysis of the gene coding for the murine cellular tumour antigen p53.

B Bienz, R Zakut-Houri, D Givol, M Oren

EMBO J. 1984 Sep; 3(9): 2179–2183. doi: 10.1002/j.1460-2075.1984.tb02110.x

PMCID:: PMC557662

Summary Page Browse PDF–1012K

Select item 5543323.

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells.

R Zakut-Houri, B Bienz-Tadmor, D Givol, M Oren

EMBO J. 1985 May; 4(5): 1251–1255. doi: 10.1002/j.1460-2075.1985.tb03768.x

PMCID:: PMC554332

Summary Page Browse PDF–1.3M

Select item 4502814.

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.

S Rowan, R L Ludwig, Y Haupt, S Bates, X Lu, M Oren, K H Vousden

EMBO J. 1996 Feb 15; 15(4): 827–838.

PMCID:: PMC450281

Summary Page Browse PDF–2.5M

Select item 4099285.

p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels

N. Gopalakrishna Iyer, Suet-Feung Chin, Hilal Ozdag, Yataro Daigo, De-En Hu, Massimiliano Cariati, Kevin Brindle, Samuel Aparicio, Carlos Caldas

Proc Natl Acad Sci U S A. 2004 May 11; 101(19): 7386–7391. Published online 2004 Apr 27. doi: 10.1073/pnas.0401002101

PMCID:: PMC409928

Article PDF–515K

Select item 3890516.

Mutation and Cancer: Statistical Study of Retinoblastoma

Alfred G. Knudson, Jr.

Proc Natl Acad Sci U S A. 1971 Apr; 68(4): 820–823. doi: 10.1073/pnas.68.4.820

PMCID:: PMC389051

Summary Page Browse PDF–676K

Select item 3228057.

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13).

O W McBride, D Merry, D Givol

Proc Natl Acad Sci U S A. 1986 Jan; 83(1): 130–134. doi: 10.1073/pnas.83.1.130

PMCID:: PMC322805

Summary Page Browse PDF–1.6M

Select item 3165428.

Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

Renbin Zhao, Kurt Gish, Maureen Murphy, Yuxin Yin, Daniel Notterman, William H. Hoffman, Edward Tom, David H. Mack, Arnold J. Levine

Genes Dev. 2000 Apr 15; 14(8): 981–993.

PMCID:: PMC316542

Article PDF–467K

Select item 2983709.

Wild-type p53 can inhibit oncogene-mediated focus formation.

D Eliyahu, D Michalovitz, S Eliyahu, O Pinhasi-Kimhi, M Oren

Proc Natl Acad Sci U S A. 1989 Nov; 86(22): 8763–8767. doi: 10.1073/pnas.86.22.8763

PMCID:: PMC298370

Summary Page Browse PDF–1.2M

Select item 23053410.

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression.

L B Owen-Schaub, W Zhang, J C Cusack, L S Angelo, S M Santee, T Fujiwara, J A Roth, A B Deisseroth, W W Zhang, E Kruzel, et al.

Mol Cell Biol. 1995 Jun; 15(6): 3032–3040. doi: 10.1128/mcb.15.6.3032

PMCID:: PMC230534

Summary PDF–438K

Select item 16451311.

Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes

Joseph Lotem, Hilah Gal, Rachel Kama, Ninette Amariglio, Gideon Rechavi, Eytan Domany, Leo Sachs, David Givol

Proc Natl Acad Sci U S A. 2003 May 27; 100(11): 6718–6723. Published online 2003 May 12. doi: 10.1073/pnas.1031695100

PMCID:: PMC164513

Article PDF–477K

Select item 14993612.

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Jian Yu, Zhenghe Wang, Kenneth W. Kinzler, Bert Vogelstein, Lin Zhang

Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4): 1931–1936. Published online 2003 Feb 6. doi: 10.1073/pnas.2627984100

PMCID:: PMC149936

Article PDF–310K

Select item 12541713.

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

Li Fang, Guangnan Li, Guizhong Liu, Sam W. Lee, Stuart A. Aaronson

EMBO J. 2001 Apr 17; 20(8): 1931–1939. doi: 10.1093/emboj/20.8.1931

PMCID:: PMC125417

Article PDF–307K

Select item 12427514.

The p53MH algorithm and its application in detecting p53-responsive genes

J. Hoh, S. Jin, T. Parrado, J. Edington, A. J. Levine, J. Ott

Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13): 8467–8472. Published online 2002 Jun 19. doi: 10.1073/pnas.132268899

PMCID:: PMC124275

Article PDF–215K

Select item 5449315.

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

W E Mercer, M T Shields, M Amin, G J Sauve, E Appella, J W Romano, S J Ullrich

Proc Natl Acad Sci U S A. 1990 Aug; 87(16): 6166–6170. doi: 10.1073/pnas.87.16.6166

PMCID:: PMC54493

Summary Page Browse PDF–1.3M

Select item 2716916.

Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines

Steve A. Maxwell, George E. Davis

Proc Natl Acad Sci U S A. 2000 Nov 21; 97(24): 13009–13014. Published online 2000 Nov 7. doi: 10.1073/pnas.230445997

PMCID:: PMC27169

Article PDF–793K

Select item 2662417.

PTGF-β, a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway

Mingjia Tan, Yixin Wang, Kunliang Guan, Yi Sun

Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1): 109–114. doi: 10.1073/pnas.97.1.109

PMCID:: PMC26624

Article PDF–246K

Select item 2446818.

Identification and classification of p53-regulated genes

Jian Yu, Lin Zhang, Paul M. Hwang, Carlo Rago, Kenneth W. Kinzler, Bert Vogelstein

Proc Natl Acad Sci U S A. 1999 Dec 7; 96(25): 14517–14522. doi: 10.1073/pnas.96.25.14517

PMCID:: PMC24468

Article PDF–333K

Select item 2333919.

Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas

Amin Fazeli, Robert G. Steen, Stephanie L. Dickinson, Dolores Bautista, William F. Dietrich, Roderick T. Bronson, Robert S. Bresalier, Eric S. Lander, Jose Costa, Robert A. Weinberg

Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19): 10199–10204. doi: 10.1073/pnas.94.19.10199