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Neoplasm of the thymus

MedGen UID:
811424
•Concept ID:
C3714644
•
Neoplastic Process
Synonyms: Neoplasm, Thymic; Neoplasm, Thymus; Neoplasms, Thymic; Neoplasms, Thymus; Thymic Neoplasm; Thymic Neoplasms; Thymic Tumor; Thymic Tumors; Thymus Neoplasm; Thymus Neoplasms; Thymus Tumor; Thymus Tumors; Tumor, Thymic; Tumor, Thymus; Tumors, Thymic; Tumors, Thymus
SNOMED CT: Tumor of thymus (127231009); Neoplasm of thymus (127231009)
 
HPO: HP:0100521
Monarch Initiative: MONDO:0005197
Orphanet: ORPHA100100

Definition

A tumor (abnormal growth of tissue) of the thymus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of the thymus

Professional guidelines

PubMed

Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y
Lung Cancer 2016 Mar;93:77-81. Epub 2016 Jan 11 doi: 10.1016/j.lungcan.2016.01.004. PMID: 26898618

Recent clinical studies

Etiology

Mutation analysis of the EGFR gene and its downstream signaling pathway in thymic carcinoma patients from a Chinese Han population.
Zhan P, Chen X, Wu XY, Hou ZB, Qian Q, Zhang Y, Zou J, Zhang YQ, Wan MY, Wang JD, Yu LK, Xie HY
Clin Respir J 2018 Feb;12(2):601-607. Epub 2016 Oct 20 doi: 10.1111/crj.12569. PMID: 27731926
Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y
Lung Cancer 2016 Mar;93:77-81. Epub 2016 Jan 11 doi: 10.1016/j.lungcan.2016.01.004. PMID: 26898618
Nationwide population-based epidemiological study of myasthenia gravis in taiwan.
Lai CH, Tseng HF
Neuroepidemiology 2010;35(1):66-71. Epub 2010 Jun 3 doi: 10.1159/000311012. PMID: 20523074Free PMC Article

Diagnosis

Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y
Lung Cancer 2016 Mar;93:77-81. Epub 2016 Jan 11 doi: 10.1016/j.lungcan.2016.01.004. PMID: 26898618
Giant thymolipoma: case report of an unusual mediastinal tumor.
Obeso Carillo GA, García Fontán EM, Cañizares Carretero MÁ
Arch Bronconeumol 2014 Dec;50(12):557-9. Epub 2014 Jun 27 doi: 10.1016/j.arbres.2013.11.028. PMID: 24985048
Ectopic thymoma presenting as a giant intrathoracic mass: a case report.
Takenaka T, Ishida T, Handa Y, Tsutsui S, Matsuda H
J Cardiothorac Surg 2012 Jul 16;7:68. doi: 10.1186/1749-8090-7-68. PMID: 22800398Free PMC Article
Asymptomatic giant mediastinal mass: a rare case of thymolipoma.
Mourad OM, Andrade FM, Abrahão P, Monnerat A, Judice LF
J Bras Pneumol 2009 Oct;35(10):1049-52. doi: 10.1590/s1806-37132009001000012. PMID: 19918636
Translocation (11;15;19): a highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients.
Toretsky JA, Jenson J, Sun CC, Eskenazi AE, Campbell A, Hunger SP, Caires A, Frantz C, Hill JL, Stamberg J
Am J Clin Oncol 2003 Jun;26(3):300-6. doi: 10.1097/01.COC.0000020960.98562.84. PMID: 12796605

Therapy

Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y
Lung Cancer 2016 Mar;93:77-81. Epub 2016 Jan 11 doi: 10.1016/j.lungcan.2016.01.004. PMID: 26898618

Prognosis

Mutation analysis of the EGFR gene and its downstream signaling pathway in thymic carcinoma patients from a Chinese Han population.
Zhan P, Chen X, Wu XY, Hou ZB, Qian Q, Zhang Y, Zou J, Zhang YQ, Wan MY, Wang JD, Yu LK, Xie HY
Clin Respir J 2018 Feb;12(2):601-607. Epub 2016 Oct 20 doi: 10.1111/crj.12569. PMID: 27731926
Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y
Lung Cancer 2016 Mar;93:77-81. Epub 2016 Jan 11 doi: 10.1016/j.lungcan.2016.01.004. PMID: 26898618
Nationwide population-based epidemiological study of myasthenia gravis in taiwan.
Lai CH, Tseng HF
Neuroepidemiology 2010;35(1):66-71. Epub 2010 Jun 3 doi: 10.1159/000311012. PMID: 20523074Free PMC Article
Translocation (11;15;19): a highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients.
Toretsky JA, Jenson J, Sun CC, Eskenazi AE, Campbell A, Hunger SP, Caires A, Frantz C, Hill JL, Stamberg J
Am J Clin Oncol 2003 Jun;26(3):300-6. doi: 10.1097/01.COC.0000020960.98562.84. PMID: 12796605
Thymoma: radiologic-pathologic correlation.
Rosado-de-Christenson ML, Galobardes J, Moran CA
Radiographics 1992 Jan;12(1):151-68. doi: 10.1148/radiographics.12.1.1734461. PMID: 1734461

Clinical prediction guides

Mutation analysis of the EGFR gene and its downstream signaling pathway in thymic carcinoma patients from a Chinese Han population.
Zhan P, Chen X, Wu XY, Hou ZB, Qian Q, Zhang Y, Zou J, Zhang YQ, Wan MY, Wang JD, Yu LK, Xie HY
Clin Respir J 2018 Feb;12(2):601-607. Epub 2016 Oct 20 doi: 10.1111/crj.12569. PMID: 27731926

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