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Seasonal allergy

MedGen UID:
42335
•Concept ID:
C0018621
•
Disease or Syndrome
Synonym: Seasonal allergic rhinitis
SNOMED CT: Seasonal allergy (444316004); Allergic rhinitis caused by pollens (21719001); Allergic rhinitis caused by pollen (21719001); Allergic rhinitis due to pollen (21719001); Pollinosis (21719001); Allergy to pollen (300910009); Allergic rhinitis due to pollens (21719001); Hay fever (21719001); Hayfever (21719001); Spasmodic rhinorrhea (367498001); Seasonal allergic rhinitis (367498001)
 
HPO: HP:0012395
Monarch Initiative: MONDO:0005324

Definition

An allergy experienced at a particular time of year when trees or grasses pollinate and elicit an allergic reaction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeasonal allergy

Professional guidelines

PubMed

Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Datusalia AK, Singh G, Yadav N, Gaun S, Manik M, Singh RK
CNS Neurol Disord Drug Targets 2022;21(10):913-925. doi: 10.2174/1871527320666210902163756. PMID: 34477536
Which is more effective for as-needed treatment of seasonal allergy symptoms: intranasal corticosteroids or oral antihistamines?
Frantz J
J Fam Pract 2002 Mar;51(3):281. PMID: 11978243

Recent clinical studies

Etiology

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation.
Kato M, Miyamoto M, Takayanagi F, Ando Y, Fujita Y, Nakayama M, Yoshihara S
J Immunol Res 2023;2023:4075264. Epub 2023 Mar 9 doi: 10.1155/2023/4075264. PMID: 36937005Free PMC Article
Allergen immunotherapy effectively reduces the risk of exacerbations and lower respiratory tract infections in both seasonal and perennial allergic asthma: a nationwide epidemiological study.
Woehlk C, Von Bülow A, Ghanizada M, Søndergaard MB, Hansen S, Porsbjerg C
Eur Respir J 2022 Nov;60(5) Epub 2022 Nov 17 doi: 10.1183/13993003.00446-2022. PMID: 35618279
Determining the minimal important differences in the RQLQ score with grass and tree allergy immunotherapy versus placebo in adults with moderate-to-severe allergy.
Blaiss MS, Gronskyte Juhl R, Siew LQC, Hammerby E, Devillier P
Allergy 2022 Jun;77(6):1843-1851. Epub 2022 Jan 22 doi: 10.1111/all.15207. PMID: 34986506Free PMC Article
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article

Diagnosis

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation.
Kato M, Miyamoto M, Takayanagi F, Ando Y, Fujita Y, Nakayama M, Yoshihara S
J Immunol Res 2023;2023:4075264. Epub 2023 Mar 9 doi: 10.1155/2023/4075264. PMID: 36937005Free PMC Article
Diagnosed Allergic Conditions in Children Aged 0-17 Years: United States, 2021.
Zablotsky B, Black LI, Akinbami LJ
NCHS Data Brief 2023 Jan;(459):1-8. PMID: 36700870
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Pollen allergic disease: pollens and its major allergens.
Taketomi EA, Sopelete MC, de Sousa Moreira PF, de Assis Machado Vieira F
Braz J Otorhinolaryngol 2006 Jul-Aug;72(4):562-7. doi: 10.1016/s1808-8694(15)31005-3. PMID: 17143438Free PMC Article
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article

Therapy

Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR).
Pavord ID, Hoyte FCL, Lindsley AW, Ambrose CS, Spahn JD, Roseti SL, Cook B, Griffiths JM, Hellqvist Å, Martin N, Llanos JP, Martin N, Colice G, Corren J
Ann Allergy Asthma Immunol 2023 Nov;131(5):587-597.e3. Epub 2023 Aug 23 doi: 10.1016/j.anai.2023.08.015. PMID: 37619779
Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Datusalia AK, Singh G, Yadav N, Gaun S, Manik M, Singh RK
CNS Neurol Disord Drug Targets 2022;21(10):913-925. doi: 10.2174/1871527320666210902163756. PMID: 34477536
Prevention of Allergic Asthma with Allergen Avoidance Measures and the Role of Exposome.
D'Amato G, Ortega OPM, Annesi-Maesano I, D'Amato M
Curr Allergy Asthma Rep 2020 Feb 26;20(3):8. doi: 10.1007/s11882-020-0901-3. PMID: 32103354
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article

Prognosis

A quality-of-life mapping function developed from a grass pollen sublingual immunotherapy trial to a tree pollen sublingual immunotherapy trial.
Dick K, Briggs A, Ohsfeldt R, Sydendal Grand T, Buchs S
J Med Econ 2020 Jan;23(1):64-69. Epub 2019 Aug 10 doi: 10.1080/13696998.2019.1649268. PMID: 31352853
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Sequence conservation predicts T cell reactivity against ragweed allergens.
Pham J, Oseroff C, Hinz D, Sidney J, Paul S, Greenbaum J, Vita R, Phillips E, Mallal S, Peters B, Sette A
Clin Exp Allergy 2016 Sep;46(9):1194-205. Epub 2016 Jul 26 doi: 10.1111/cea.12772. PMID: 27359111Free PMC Article
Ultra-short-course seasonal allergy vaccine (Pollinex Quattro).
McCormack PL, Wagstaff AJ
Drugs 2006;66(7):931-8. doi: 10.2165/00003495-200666070-00004. PMID: 16740007
Allergen biodistribution in humans.
Bagnasco M, Morbelli S, Altrinetti V, Falagiani P, Mariani G, Passalacqua G
Chem Immunol Allergy 2003;82:33-43. doi: 10.1159/000071538. PMID: 12947990

Clinical prediction guides

Allergen immunotherapy effectively reduces the risk of exacerbations and lower respiratory tract infections in both seasonal and perennial allergic asthma: a nationwide epidemiological study.
Woehlk C, Von Bülow A, Ghanizada M, Søndergaard MB, Hansen S, Porsbjerg C
Eur Respir J 2022 Nov;60(5) Epub 2022 Nov 17 doi: 10.1183/13993003.00446-2022. PMID: 35618279
Determining the minimal important differences in the RQLQ score with grass and tree allergy immunotherapy versus placebo in adults with moderate-to-severe allergy.
Blaiss MS, Gronskyte Juhl R, Siew LQC, Hammerby E, Devillier P
Allergy 2022 Jun;77(6):1843-1851. Epub 2022 Jan 22 doi: 10.1111/all.15207. PMID: 34986506Free PMC Article
Sensitization against Fungi in Patients with Airway Allergies over 20 Years in Germany.
Forkel S, Beutner C, Schröder SS, Bader O, Gupta S, Fuchs T, Schön MP, Geier J, Buhl T
Int Arch Allergy Immunol 2021;182(6):515-523. Epub 2021 Mar 29 doi: 10.1159/000512230. PMID: 33780961Free PMC Article
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Sequence conservation predicts T cell reactivity against ragweed allergens.
Pham J, Oseroff C, Hinz D, Sidney J, Paul S, Greenbaum J, Vita R, Phillips E, Mallal S, Peters B, Sette A
Clin Exp Allergy 2016 Sep;46(9):1194-205. Epub 2016 Jul 26 doi: 10.1111/cea.12772. PMID: 27359111Free PMC Article

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