African degenerative visceral leiomyopathy (ADL) is a distinctive visceral myopathy with onset in childhood. It presents as intestinal pseudoobstruction with a massive megacolon due to degeneration of smooth muscle without aganglionosis (Van Rensburg et al., 2012). Some patients have megaureter and megacystis (Rode et al., 1992). [from
OMIM]