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Gonorrhea

MedGen UID:
9077
•Concept ID:
C0018081
•
Disease or Syndrome
Synonym: Neisseria gonorrhoeae Infection
SNOMED CT: GC - Gonococcus infection (15628003); Clap (15628003); GCI - Gonococcal infection (15628003); Gonorrhea (15628003); Gonococcal infection (15628003)
 
Monarch Initiative: MONDO:0004277
Orphanet: ORPHA100642

Definition

An infection that is caused by Gonococcus. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Antimicrobial Resistance in Neisseria gonorrhoeae and Treatment of Gonorrhea.
Unemo M, Golparian D, Eyre DW
Methods Mol Biol 2019;1997:37-58. doi: 10.1007/978-1-4939-9496-0_3. PMID: 31119616
Conjunctivitis: a systematic review of diagnosis and treatment.
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article

Recent clinical studies

Etiology

An Update on Gonorrhea and Chlamydia.
Dutra K, Lazenby G
Obstet Gynecol Clin North Am 2023 Jun;50(2):299-310. Epub 2023 Apr 4 doi: 10.1016/j.ogc.2023.02.004. PMID: 37149311
Gonorrheal Diseases.
Perry M, Allison BA
Pediatr Rev 2018 Aug;39(8):427-429. doi: 10.1542/pir.2017-0120. PMID: 30068746
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616
Septic arthritis.
García-Arias M, Balsa A, Mola EM
Best Pract Res Clin Rheumatol 2011 Jun;25(3):407-21. doi: 10.1016/j.berh.2011.02.001. PMID: 22100289
Gonorrhea.
Judson FN
Med Clin North Am 1990 Nov;74(6):1353-66. doi: 10.1016/s0025-7125(16)30485-0. PMID: 2123279

Diagnosis

Ocular Gonorrhea.
Suyama Y, Akiyama R
N Engl J Med 2022 Apr 28;386(17):e46. Epub 2022 Apr 23 doi: 10.1056/NEJMicm2117893. PMID: 35452200
Gonorrheal Diseases.
Perry M, Allison BA
Pediatr Rev 2018 Aug;39(8):427-429. doi: 10.1542/pir.2017-0120. PMID: 30068746
Gonorrhea.
Morgan MK, Decker CF
Dis Mon 2016 Aug;62(8):260-8. Epub 2016 Apr 20 doi: 10.1016/j.disamonth.2016.03.009. PMID: 27107780
Gonorrhea: new challenges.
Skerlev M, Čulav-Košćak I
Clin Dermatol 2014 Mar-Apr;32(2):275-81. doi: 10.1016/j.clindermatol.2013.08.010. PMID: 24559563
Gonorrhea.
Judson FN
Med Clin North Am 1990 Nov;74(6):1353-66. doi: 10.1016/s0025-7125(16)30485-0. PMID: 2123279

Therapy

Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men and male STD patients in China: the PIONEER pragmatic, cluster randomized controlled trial protocol.
Marley G, Tan RKJ, Wu D, Wang T, Sun M, Sheng Q, Holly ME, Hlatshwako TG, Wang C, Tang W, Ramaswamy R, Yang L, Luo D, Sylvia SS, Gray K, Van Duin D, Zheng H, Tucker JD
BMC Public Health 2023 Jun 20;23(1):1182. doi: 10.1186/s12889-023-16095-8. PMID: 37337181Free PMC Article
Epidemiology, Treatments, and Vaccine Development for Antimicrobial-Resistant Neisseria gonorrhoeae: Current Strategies and Future Directions.
Lin EY, Adamson PC, Klausner JD
Drugs 2021 Jul;81(10):1153-1169. Epub 2021 Jun 7 doi: 10.1007/s40265-021-01530-0. PMID: 34097283Free PMC Article
Clinical update.
Haddow L, Herbert S
Sex Transm Infect 2015 Mar;91(2):150. doi: 10.1136/sextrans-2014-051963. PMID: 25698792
Ofloxacin.
Tunkel AR, Scheld WM
Infect Control Hosp Epidemiol 1991 Sep;12(9):549-57. doi: 10.1086/646408. PMID: 1940278
Ceftriaxone: a third-generation cephalosporin.
Nahata MC, Barson WJ
Drug Intell Clin Pharm 1985 Dec;19(12):900-6. doi: 10.1177/106002808501901203. PMID: 3910386

Prognosis

Analysis and prediction of the incidence and prevalence trends of gonorrhea in China.
Chen X, Chen S, Li C, Shi L, Zhu Y, Yao Y
Hum Vaccin Immunother 2023 Aug;19(2):2256907. Epub 2023 Oct 9 doi: 10.1080/21645515.2023.2256907. PMID: 37807860Free PMC Article
Gonorrhoea in Poland in 2019-2020.
Zakrzewska K, Niedźwiedzka-Stadnik M
Przegl Epidemiol 2022;76(4):591-603. doi: 10.32394/pe.76.54. PMID: 37017460
Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018.
Kreisel KM, Spicknall IH, Gargano JW, Lewis FMT, Lewis RM, Markowitz LE, Roberts H, Johnson AS, Song R, St Cyr SB, Weston EJ, Torrone EA, Weinstock HS
Sex Transm Dis 2021 Apr 1;48(4):208-214. doi: 10.1097/OLQ.0000000000001355. PMID: 33492089Free PMC Article
Gonorrhea: new challenges.
Skerlev M, Čulav-Košćak I
Clin Dermatol 2014 Mar-Apr;32(2):275-81. doi: 10.1016/j.clindermatol.2013.08.010. PMID: 24559563
Gonorrhea: update.
Little JW
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Feb;101(2):137-43. doi: 10.1016/j.tripleo.2005.05.077. PMID: 16448912

Clinical prediction guides

Analysis and prediction of the incidence and prevalence trends of gonorrhea in China.
Chen X, Chen S, Li C, Shi L, Zhu Y, Yao Y
Hum Vaccin Immunother 2023 Aug;19(2):2256907. Epub 2023 Oct 9 doi: 10.1080/21645515.2023.2256907. PMID: 37807860Free PMC Article
Immune responses to Neisseria gonorrhoeae and implications for vaccine development.
Belcher T, Rollier CS, Dold C, Ross JDC, MacLennan CA
Front Immunol 2023;14:1248613. Epub 2023 Aug 17 doi: 10.3389/fimmu.2023.1248613. PMID: 37662926Free PMC Article
Recent Progress Towards a Gonococcal Vaccine.
Maurakis SA, Cornelissen CN
Front Cell Infect Microbiol 2022;12:881392. Epub 2022 Apr 11 doi: 10.3389/fcimb.2022.881392. PMID: 35480233Free PMC Article
Prediction model for gonorrhea, chlamydia, and trichomoniasis in the emergency department.
Sheele JM, Niforatos JD, Elkins JM, Campos SC, Thompson CL
Am J Emerg Med 2022 Jan;51:313-319. Epub 2021 Nov 7 doi: 10.1016/j.ajem.2021.11.004. PMID: 34798573
Spectinomycin.
Holloway WJ
Med Clin North Am 1982 Jan;66(1):169-73. PMID: 6460907

Recent systematic reviews

Long-Acting Reversible Contraception, Condom Use, and Sexually Transmitted Infections: A Systematic Review and Meta-analysis.
Steiner RJ, Pampati S, Kortsmit KM, Liddon N, Swartzendruber A, Pazol K
Am J Prev Med 2021 Nov;61(5):750-760. Epub 2021 Sep 16 doi: 10.1016/j.amepre.2021.04.032. PMID: 34686301Free PMC Article
The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.
Tamarelle J, Thiébaut ACM, de Barbeyrac B, Bébéar C, Ravel J, Delarocque-Astagneau E
Clin Microbiol Infect 2019 Jan;25(1):35-47. Epub 2018 May 3 doi: 10.1016/j.cmi.2018.04.019. PMID: 29729331Free PMC Article
Conjunctivitis: a systematic review of diagnosis and treatment.
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article
Bacterial conjunctivitis.
Epling J
BMJ Clin Evid 2012 Feb 20;2012 PMID: 22348418Free PMC Article
Bacterial conjunctivitis.
Epling J
BMJ Clin Evid 2010 Mar 15;2010 PMID: 21718563Free PMC Article

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