U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from PMC

Lichen disease

MedGen UID:
507920
•Concept ID:
C0023643
•
Disease or Syndrome
Synonyms: Lichen; lichen; Lichen condition; lichen condition; lichen disease
SNOMED CT: Lichen (88996004); Lichen condition (88996004)
 
Monarch Initiative: MONDO:0006570

Definition

A long-term skin condition that mainly affects the skin of the genitals. It usually causes itching and white patches to appear on the affected skin. [from MONDO]

Professional guidelines

PubMed

Keratosis pilaris: an update and approach to management.
Kodali N, Patel VM, Schwartz RA
Ital J Dermatol Venerol 2023 Jun;158(3):217-223. Epub 2023 May 11 doi: 10.23736/S2784-8671.23.07594-1. PMID: 37166753
2022 European guideline for the management of balanoposthitis.
Edwards SK, Bunker CB, van der Snoek EM, van der Meijden WI
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1104-1117. Epub 2023 Mar 21 doi: 10.1111/jdv.18954. PMID: 36942977
Contact Dermatitis: Classifications and Management.
Li Y, Li L
Clin Rev Allergy Immunol 2021 Dec;61(3):245-281. Epub 2021 Jul 15 doi: 10.1007/s12016-021-08875-0. PMID: 34264448

Recent clinical studies

Etiology

Vulvar-vaginal-gingival-otic syndrome.
Shao Y, Sun K, Yang M, Chang J
Exp Dermatol 2024 Jan;33(1):e14912. Epub 2023 Aug 23 doi: 10.1111/exd.14912. PMID: 37612855
Review of Nail Lichen Planus: Epidemiology, Pathogenesis, Diagnosis, and Treatment.
Gupta MK, Lipner SR
Dermatol Clin 2021 Apr;39(2):221-230. Epub 2021 Feb 10 doi: 10.1016/j.det.2020.12.002. PMID: 33745635
Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies.
Melguizo-Rodríguez L, Costela-Ruiz VJ, Manzano-Moreno FJ, Ruiz C, Illescas-Montes R
Int J Mol Sci 2020 Jul 21;21(14) doi: 10.3390/ijms21145173. PMID: 32708341Free PMC Article
Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis.
Tziotzios C, Lee JYW, Brier T, Saito R, Hsu CK, Bhargava K, Stefanato CM, Fenton DA, McGrath JA
J Am Acad Dermatol 2018 Nov;79(5):789-804. doi: 10.1016/j.jaad.2018.02.010. PMID: 30318136

Diagnosis

Extragenital lichen sclerosus: A comprehensive review.
Arif T, Fatima R, Sami M
Australas J Dermatol 2022 Nov;63(4):452-462. Epub 2022 Aug 11 doi: 10.1111/ajd.13890. PMID: 35950883
Review of Nail Lichen Planus: Epidemiology, Pathogenesis, Diagnosis, and Treatment.
Gupta MK, Lipner SR
Dermatol Clin 2021 Apr;39(2):221-230. Epub 2021 Feb 10 doi: 10.1016/j.det.2020.12.002. PMID: 33745635
Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis.
Tziotzios C, Lee JYW, Brier T, Saito R, Hsu CK, Bhargava K, Stefanato CM, Fenton DA, McGrath JA
J Am Acad Dermatol 2018 Nov;79(5):789-804. doi: 10.1016/j.jaad.2018.02.010. PMID: 30318136
Interface dermatitis.
Joshi R
Indian J Dermatol Venereol Leprol 2013 May-Jun;79(3):349-59. doi: 10.4103/0378-6323.110780. PMID: 23619439
Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation.
Ismail SB, Kumar SK, Zain RB
J Oral Sci 2007 Jun;49(2):89-106. doi: 10.2334/josnusd.49.89. PMID: 17634721

Therapy

Frontal Fibrosing Alopecia - a review and a practical guide for clinicians.
Kępińska K, Jałowska M, Bowszyc-Dmochowska M
Ann Agric Environ Med 2022 Jun 24;29(2):169-184. Epub 2021 Aug 31 doi: 10.26444/aaem/141324. PMID: 35767748
Review of Nail Lichen Planus: Epidemiology, Pathogenesis, Diagnosis, and Treatment.
Gupta MK, Lipner SR
Dermatol Clin 2021 Apr;39(2):221-230. Epub 2021 Feb 10 doi: 10.1016/j.det.2020.12.002. PMID: 33745635
Update on the classification and treatment of localized scleroderma.
Bielsa Marsol I
Actas Dermosifiliogr 2013 Oct;104(8):654-66. Epub 2013 Aug 13 doi: 10.1016/j.adengl.2012.10.012. PMID: 23948159
Therapeutic roles of curcumin: lessons learned from clinical trials.
Gupta SC, Patchva S, Aggarwal BB
AAPS J 2013 Jan;15(1):195-218. Epub 2012 Nov 10 doi: 10.1208/s12248-012-9432-8. PMID: 23143785Free PMC Article
Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation.
Ismail SB, Kumar SK, Zain RB
J Oral Sci 2007 Jun;49(2):89-106. doi: 10.2334/josnusd.49.89. PMID: 17634721

Prognosis

Frontal Fibrosing Alopecia - a review and a practical guide for clinicians.
Kępińska K, Jałowska M, Bowszyc-Dmochowska M
Ann Agric Environ Med 2022 Jun 24;29(2):169-184. Epub 2021 Aug 31 doi: 10.26444/aaem/141324. PMID: 35767748
Lichen planus - a clinical guide.
Solimani F, Forchhammer S, Schloegl A, Ghoreschi K, Meier K
J Dtsch Dermatol Ges 2021 Jun;19(6):864-882. Epub 2021 Jun 7 doi: 10.1111/ddg.14565. PMID: 34096678
Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis.
Tziotzios C, Lee JYW, Brier T, Saito R, Hsu CK, Bhargava K, Stefanato CM, Fenton DA, McGrath JA
J Am Acad Dermatol 2018 Nov;79(5):789-804. doi: 10.1016/j.jaad.2018.02.010. PMID: 30318136
Lichen planus pigmentosus and its variants: review and update.
Robles-Méndez JC, Rizo-Frías P, Herz-Ruelas ME, Pandya AG, Ocampo Candiani J
Int J Dermatol 2018 May;57(5):505-514. Epub 2017 Oct 26 doi: 10.1111/ijd.13806. PMID: 29076159

Clinical prediction guides

Nail psoriasis and nail lichen planus: Updates on diagnosis and management.
Hwang JK, Grover C, Iorizzo M, Lebwohl MG, Piraccini BM, Rigopoulos DG, Lipner SR
J Am Acad Dermatol 2024 Mar;90(3):585-596. Epub 2023 Nov 24 doi: 10.1016/j.jaad.2023.11.024. PMID: 38007038
Extragenital lichen sclerosus: A comprehensive review.
Arif T, Fatima R, Sami M
Australas J Dermatol 2022 Nov;63(4):452-462. Epub 2022 Aug 11 doi: 10.1111/ajd.13890. PMID: 35950883
Autoimmunity in Segmental Vitiligo.
Speeckaert R, Lambert J, Bulat V, Belpaire A, Speeckaert M, van Geel N
Front Immunol 2020;11:568447. Epub 2020 Oct 27 doi: 10.3389/fimmu.2020.568447. PMID: 33193342Free PMC Article
Noninfectious Penile Lesions.
Teichman JMH, Mannas M, Elston DM
Am Fam Physician 2018 Jan 15;97(2):102-110. PMID: 29365226
Noninfectious penile lesions.
Teichman JM, Sea J, Thompson IM, Elston DM
Am Fam Physician 2010 Jan 15;81(2):167-74. PMID: 20082512

Recent systematic reviews

Curcumin and Curcuma longa Extract in the Treatment of 10 Types of Autoimmune Diseases: A Systematic Review and Meta-Analysis of 31 Randomized Controlled Trials.
Zeng L, Yang T, Yang K, Yu G, Li J, Xiang W, Chen H
Front Immunol 2022;13:896476. Epub 2022 Aug 1 doi: 10.3389/fimmu.2022.896476. PMID: 35979355Free PMC Article
Worldwide prevalence of oral lichen planus: A systematic review and meta-analysis.
González-Moles MÁ, Warnakulasuriya S, González-Ruiz I, González-Ruiz L, Ayén Á, Lenouvel D, Ruiz-Ávila I, Ramos-García P
Oral Dis 2021 May;27(4):813-828. Epub 2020 Apr 2 doi: 10.1111/odi.13323. PMID: 32144836
Diabetes mellitus and oral cancer/oral potentially malignant disorders: A systematic review and meta-analysis.
Ramos-Garcia P, Roca-Rodriguez MDM, Aguilar-Diosdado M, Gonzalez-Moles MA
Oral Dis 2021 Apr;27(3):404-421. Epub 2020 Feb 18 doi: 10.1111/odi.13289. PMID: 31994293
Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review.
Weidner T, Illing T, Elsner P
Am J Clin Dermatol 2017 Oct;18(5):629-642. doi: 10.1007/s40257-017-0278-9. PMID: 28342017
Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.
Vaughn AR, Branum A, Sivamani RK
Phytother Res 2016 Aug;30(8):1243-64. Epub 2016 May 23 doi: 10.1002/ptr.5640. PMID: 27213821

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...