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Items: 3

1.

Hemolytic-uremic syndrome

A thrombotic microangiopathy with presence of non-immune, intravascular hemolytic anemia, thrombocytopenia and acute kidney injury. A vicious cycle of complement activation, endothelial cell damage, platelet activation, and thrombosis is the hallmark of the disease. [from HPO]

MedGen UID:
42403
Concept ID:
C0019061
Disease or Syndrome
2.

Thrombocytopenic purpura

Purpura associated with a reduction in circulating blood platelets which can result from a variety of factors. [from NCI]

MedGen UID:
208992
Concept ID:
C0857305
Disease or Syndrome
3.

Thrombotic thrombocytopenic purpura

An aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of a congenital (cTTP) and acquired, immune-mediated (iTTP) form. [from ORDO]

MedGen UID:
48266
Concept ID:
C0034155
Disease or Syndrome
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