U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from PMC

    • Showing Current items.

    ppp3ca.S protein phosphatase 3, catalytic subunit, alpha isozyme S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 380507, updated on 11-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ppp3ca.S
    Official Full Name
    protein phosphatase 3, catalytic subunit, alpha isozyme S homeolog
    Primary source
    Xenbase:XB-GENE-17332924
    Locus tag
    XELAEV_18009418mg
    See related
    EnsemblRapid:ENSXLAG00005030645
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    caln; ccn1; cna1; calna; ppp2b; calna1; ppp3ca; calcineurin
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 1S
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (62804534..62914270)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (62347107..62457036)

    Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108704457 Neighboring gene solute carrier family 39 (zinc transporter), member 8 S homeolog Neighboring gene cell wall protein IFF6-like Neighboring gene DNA damage inducible transcript 4 like S homeolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular cloning and expression profile of Xenopus calcineurin A subunit(1). Saneyoshi T, et al. Biochim Biophys Acta, 2000 Dec 11. PMID 11118649
    2. Regulation of calcineurin by growth cone calcium waves controls neurite extension. Lautermilch NJ, et al. J Neurosci, 2000 Jan 1. PMID 10627609, Free PMC Article
    3. Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20. Heim A, et al. EMBO Rep, 2018 Dec. PMID 30373936, Free PMC Article
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC52521

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin-dependent protein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within calcineurin-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of calcineurin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein phosphatase 3, catalytic subunit, alpha isoform
    Names
    calcineurin A alpha
    NP_001080813.1
    XP_018089403.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087344.1 → NP_001080813.1  protein phosphatase 3, catalytic subunit, alpha isoform

      See identical proteins and their annotated locations for NP_001080813.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049001
      UniProtKB/TrEMBL
      A0A974I0T0, O57438, Q801N4
      Related
      ENSXLAP00005092914.1, ENSXLAT00005094597.1
      Conserved Domains (2) summary
      smart00156
      Location:58 → 329
      PP2Ac; Protein phosphatase 2A homologues, catalytic domain
      cd07416
      Location:41 → 345
      MPP_PP2B; PP2B, metallophosphatase domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      62804534..62914270
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018233914.2 → XP_018089403.1  protein phosphatase 3, catalytic subunit, alpha isoform isoform X1

      UniProtKB/TrEMBL
      A0A1L8HMB2, A0A974DUG0, Q9DEF7
      Related
      ENSXLAP00005093009.1, ENSXLAT00005094692.1
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous