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    rad17 RFC-like checkpoint protein Rad17 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541643, updated on 15-Mar-2024

    Summary

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    Gene symbol
    rad17
    Gene description
    RFC-like checkpoint protein Rad17
    Primary source
    PomBase:SPAC14C4.13
    Locus tag
    SPAC14C4.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rad17 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (5253235..5255892)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative polyphosphate synthetase Neighboring gene clr6 L-associated factor 1 Laf1 Neighboring gene miscRNA Neighboring gene F1-ATPase alpha subunit Neighboring gene putative dipeptidyl peptidase Neighboring gene cofilin/tropomyosin family protein abp1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. al-Khodairy F, et al. Mol Biol Cell, 1994 Feb. PMID 8019001, Free PMC Article
    2. Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints. Shimada M, et al. Mol Biol Cell, 1999 Dec. PMID 10588638, Free PMC Article
    3. Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures. Kai M, et al. Mol Cell Biol, 2001 May. PMID 11313455, Free PMC Article
    4. Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination. Saito TT, et al. Nucleic Acids Res, 2004. PMID 15210864, Free PMC Article
    5. Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe. Harris S, et al. J Cell Sci, 2003 Sep 1. PMID 12865439

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables ATP hydrolysis activity IC
    Inferred by Curator
    more info
    		  
    contributes_to DNA clamp loader activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic G2 DNA damage checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic intra-S DNA damage checkpoint signaling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitotic intra-S DNA damage checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in telomere maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rad17 RFC-like complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, telomeric repeat region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RFC-like checkpoint protein Rad17

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5253235..5255892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020350.2 → NP_594918.1  RFC-like checkpoint protein Rad17 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594918.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P50531
      Conserved Domains (2) summary
      cd00009
      Location:91 → 248
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      TIGR00602
      Location:1 → 595
      rad24; checkpoint protein rad24
    Nucleotide Protein
    Heading Accession and Version

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