GEO DataSet Links for PMC (Select 1933515) - GEO DataSets

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Items: 2

Select item 2000075081.

Identification of LEDGF-responsive genes in Jurkat cells

(Submitter supplied) The LEDGF transcript from the PSIP1 gene was knocked down in Jurkat cells using RNAi technology. The resulting Jurkat-derived cell line (Jurkat-siJK2) was compared to a control cell line (wild type Jurkat) using microarray analysis. Genes identified as being modulated by LEDGF were preferential targets of HIV integration. Keywords: effects of gene knockdown

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2883
Platform:: GPL570
6 Samples

Download data: CEL, CHP, EXP

Series

Accession:: GSE7508

ID:: 200007508

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28832.

LEDGF/p75 transcription factor deficiency effect on T-cell line

Analysis of Jurkat T-cells depleted for the LEDGF/p75 transcription factor. LEDGF/p75 is involved in targeting HIV DNA integration. Results provide insight into the mechanisms controlling HIV integration.