NCGC[SourceName] - PubChem BioAssay Results

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NCGC[SourceName](322)
Information and surveillance systems and community health: building the public health info...Information and surveillance systems and community health: building the public health information infrastructure.
Mutation of POLG is associated with progressive external ophthalmoplegia characterized by ...Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions.
Developing national performance standards for local public health systems.Developing national performance standards for local public health systems.
Behaviors associated with ultraviolet radiation exposure in a cohort of adult survivors of...Behaviors associated with ultraviolet radiation exposure in a cohort of adult survivors of childhood and adolescent cancer: a report from the Childhood Cancer Survivor Study.

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1:	AID: 2169	Summary	Related BioAssays, Target, Literature, Other Links
	Probe Development Summary of Inhibitors of 15-hLO-1 (15-human lipoxygenase 1) [Summary] Source: NCGC Protein Target: 15-lipoxygenase [Homo sapiens] [gi: 1832253] Substances Active: 0; Tested: 0 Description: Source: NIH Chemical Genomics Center [NCGC] Assay Submitter: Holman, T.R., University of California, Santa Cruz Screening Center PI: Christopher P. Austin,... more

2:	AID: 2164	Summary	Related BioAssays, Target, Literature, Other Links
	Probe Development Summary of Inhibitors of 12-hLO (12-human lipoxygenase) [Summary] Source: NCGC Protein Target: arachidonate 12-lipoxygenase [Homo sapiens] [gi: 154426292] Substances Active: 0; Tested: 0 Description: Source: NIH Chemical Genomics Center [NCGC] Assay Submitter: Holman, T.R., University of California, Santa Cruz Screening Center PI: Christopher P. Austin,... more

3:	AID: 2163
	Source: NCGC Deposit Date: 2009/11/25 \| Hold-until Date: 2010/05/14

4:	AID: 2162
	Source: NCGC Deposit Date: 2009/11/25 \| Hold-until Date: 2010/05/14

5:	AID: 2161	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay [Confirmatory] Source: NCGC Protein Target: Chain A, Use Of Papain As A Model For The Structure-Based Design Of Cathepsin K Inhibitors. Crystal Structures Of Two Papain Inhibitor Complexes Demonstrate Binding To S'-Subsites. [gi: 157830437] Compounds Active: 159; Tested: 393 Description: Assay Provider: Shoichet, Brian; University of California, San Fancisco Screening Center PI: Austin, C.P. Screening Center: NIH Chemical Genomics Center... more

6:	AID: 2158	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	Confirmation qHTS Assay for Inhibitors of Cruzain [Confirmatory] Source: NCGC Protein Target: Chain A, High Resolution Crystal Structure Analysis Of Cruzain Non- Covalently Bound To A Hydroxymethyl Ketone Inhibitor (I) [gi: 27573888] Compounds Active: 287; Tested: 572 Description: Assay Provider: Shoichet, Brian; University of California, San Fancisco Screening Center PI: Austin, C.P. Screening Center: NIH Chemical Genomics Center... more

7:	AID: 2157	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	Confirmation qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [Confirmatory] Source: NCGC Protein Target: 15-lipoxygenase [Homo sapiens] [gi: 1832253] Compounds Active: 12; Tested: 54 Description: Assay Provider: Holman, T.R., University of California, Santa Cruz Screening Center PI: Austin, Christopher P. Screening Center: NIH Chemical Genomics... more

8:	AID: 2155	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	Cuvette-Based Assay fo Inhibitors of 15-hLO-1 (15-human lipoxygenase 1) [Confirmatory] Source: NCGC Protein Target: 15-lipoxygenase [Homo sapiens] [gi: 1832253] Compounds Active: 20; Tested: 20 Description: Assay Provider: Holman, T.R., University of California, Santa Cruz Screening Center PI: Austin, Christopher P. Screening Center: NIH Chemical Genomics... more

AID: 1997

Summary | Data (Active)

qHTS for Inhibitors of CDC-like Kinase 4: Summary [Summary]
Source: NCGC
Protein Target: CDC-like kinase 4 [Homo sapiens] [gi: 10190706]
Compounds Probe: 2; Active: 2; Tested: 2
List of Probes:

CID 3234998

CID 3232621

Description: NIH Molecular Libraries Probe Production Centers Network [MLPCN] NIH Chemical Genomics Center [NCGC] MLPCN Grant: 1R03MH084827-01 Assay Submitter (PI):... more

10:	AID: 2147	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [Confirmatory] Source: NCGC Protein Target: Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi: 221046486] Compounds Active: 3522; Tested: 226938 Description: Assay Provider: Structural Genomics Consortium [SGC] Screening Center PI: Austin, C.P. Screening Center: NIH Chemical Genomics Center [NCGC] The fine... more

11:	AID: 1541	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Secondary assay for Activators of Human Liver Pyruvate Kinase [Confirmatory] Source: NCGC Protein Target: pyruvate kinase, liver and RBC isoform 2 [Homo sapiens] [gi: 32967597] Compounds Active: 1; Tested: 2 Description: Confirmatory assay NIH Chemical Genomics Center [NCGC] Matthew G. Vander Heiden, M.D., Ph.D. [Harvard Medical School, 77 Avenue Louis Pasteur, Boston,... more

12:	AID: 2120	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response [Confirmatory] Source: NCGC Protein Target: hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi: 32879895] Compounds Active: 6; Tested: 1335 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Screening Centers Network [MLSCN] National Institutes of Environmental Health Sciences [NIEHS]... more

13:

AID: 2095

Summary | Data (Active)

qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase: Summary [Summary]
Source: NCGC
Protein Target: pyruvate kinase, muscle isoform M2 [Homo sapiens] [gi: 33286418]
Compounds Probe: 2; Active: 2; Tested: 2
List of Probes:

CID 654376

CID 650361

Description: NIH Chemical Genomics Center [NCGC] Matthew G. Vander Heiden, M.D., Ph.D. [Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115] MLPCN Grant:... more

14:	AID: 2115	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase [Confirmatory] Source: NCGC Protein Target: acid alpha-glucosidase preproprotein [Homo sapiens] [gi: 119393891] Compounds Active: 3; Tested: 296 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Probe Production centers Network [MLPCN] MLPCN Grant: 1R03MH084841-01 Assay Submitter (PI):... more

15:	AID: 2114	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	qHTS Assay for Inhibitors of Human Galactokinase (GALK): Summary [Summary] Source: NCGC Protein Target: galactokinase 1 [Homo sapiens] [gi: 4503895] Compounds Active: 42; Tested: 159 Description: NIH Molecular Libraries Probe Production Centers Network [MLPCN] NIH Chemical Genomics Center [NCGC] MLPCN Grant: R03 MH085689-01 Assay Submitter (PI):... more

16:	AID: 2113	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [Confirmatory] Source: NCGC Protein Target: acid alpha-glucosidase preproprotein [Homo sapiens] [gi: 119393891] Compounds Active: 40; Tested: 379 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Probe Production centers Network [MLPCN] MLPCN Grant: 1R03MH084841-01 Assay Submitter (PI):... more

17:	AID: 2112	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [Confirmatory] Source: NCGC Protein Target: acid alpha-glucosidase preproprotein [Homo sapiens] [gi: 119393891] Compounds Active: 15; Tested: 232187 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Probe Production Centers Network [MLPCN] MLPCN Grant: R03 MH084841-01 Assay Submitter (PI):... more

18:	AID: 2111	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate Using an Alternate Red Fluorescent Susbtrate [Confirmatory] Source: NCGC Protein Target: acid alpha-glucosidase preproprotein [Homo sapiens] [gi: 119393891] Compounds Active: 39; Tested: 59 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Probe Production centers Network [MLPCN] MLPCN Grant: 1R03MH084841-01 Assay Submitter (PI):... more

19:	AID: 2110	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase Using an Alternate Red Fluorescent Susbtrate [Confirmatory] Source: NCGC Protein Target: acid alpha-glucosidase preproprotein [Homo sapiens] [gi: 119393891] Compounds Active: 41; Tested: 70 Description: NIH Chemical Genomics Center [NCGC] NIH Molecular Libraries Probe Production centers Network [MLPCN] MLPCN Grant: 1R03MH084841-01 Assay Submitter (PI):... more

20:	AID: 1782	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Other Links
	Confirmation Concentration-Response Assay for Activators of Human Reticulocyte Pyruvate Kinase [Confirmatory] Source: NCGC Protein Target: pyruvate kinase, liver and RBC isoform 1 [Homo sapiens] [gi: 10835121] Compounds Active: 1; Tested: 99 Description: Confirmatory assay NIH Chemical Genomics Center [NCGC] Wael M. Rabeh, Lyudmila Nedyalkova and Hee-Wan Park [Structural Genomics Consortium, 100 College... more