yeast cell cycle control - PubChem BioAssay Results

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yeast cell cycle control(20)
Phase analysis of circadian-related genes in two tissues.Phase analysis of circadian-related genes in two tissues.
Leptotrichia buccalis DSM 1135, whole genome shotgun sequence Leptotrichia buccalis DSM 1135, whole genome shotgun sequence
Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear r...Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear receptors.
Concordance of residual dipolar couplings, backbone order parameters and crystallographic ...Concordance of residual dipolar couplings, backbone order parameters and crystallographic B-factors for a small alpha/beta protein: a unified picture of high probability, fast atomic motions in proteins.

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1:	AID: 2125	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Determining Proliferation Inhibition by 26S Proteasomes Inhibitors: Panel Secondary Assay for disassembly of the 26S Proteasome Source: NMMLSC Compounds Active: 2; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

2:	AID: 1314	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Flow Cytometric Sic1-GFP Fusion Protein Degradation Assay with overexpression of Cln2: Secondary Assay for disassembly of the 26S Proteasome Source: NMMLSC Compounds Active: 3; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

3:	AID: 1313	Summary \| Data (All)	Related BioAssays, Chemicals, Literature, Other Links
	Flow Cytometric Sic1-GFP Fusion Protein Degradation Assay: Secondary Assay for disassembly of the 26S Proteasome Source: NMMLSC Compounds Active: 0; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

4:	AID: 1312	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Flow Cytometric Mutated at Ubiquitination Sites Sic1-GFP Fusion Protein Degradation Assay: Secondary Assay for disassembly of the 26S Proteasome Source: NMMLSC Compounds Active: 2; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

5:	AID: 1311	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Flow Cytometric Mutated at Ubiquitination Sites Sic1-GFP Fusion Protein Degradation Assay with overexpression of Cln2: Secondary Assay for disassembly of the 26S Proteasome Source: NMMLSC Compounds Active: 3; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

6:	AID: 1083	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature
	Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [Confirmatory] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 32; Tested: 161 Description: List of compounds to be tested: 184 purchased chemical analogs of selected hits identified in the in vitro PLK1-PBD binding primary screen AID 693, and... more

7:	AID: 1082	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature
	Concentration Response fluorescence polarization-based assay to test PMLSC Chemistry Core synthesized analogs of 861574, a confirmed hit from the Polo box domain (PBD) of Plk1 Primary HTS. [Confirmatory] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 1; Tested: 37 Description: List of compounds to be tested: 37 component starting materials and chemical analogs of the 861574 hit identified in the in vitro PLK1-PBD binding primary... more

8:	AID: 1057	Summary \| Data (All)	Related BioAssays, Chemicals, Target, Literature
	Concentration Response fluorescence polarization-based assay to test PMLSC Chemistry Core synthesized analogs of confirmed hits from the Polo box domain (PBD) of Plk1 Primary HTS. [Confirmatory] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 0; Tested: 33 Description: List of compounds to be tested: 33 component starting materials and chemical analogs of the hits identified in the in vitro PLK1-PBD binding primary screen... more

9:	AID: 877	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature
	Concentration Response fluorescence polarization-based assay to confirm small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS. [Confirmatory] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 15; Tested: 117 Description: List of compounds to be tested: Compounds that met the active criterion of Z-score is </= -3 in the in vitro PLK1-PBD binding primary screen AID 693,... more

10:	AID: 2132	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Determining Proteolysis and Inhibition of 26S Proteasomes with Fluorogenic Peptides: Secondary Assay for disassembly of the 26S Proteasome [Primary Screening] Source: NMMLSC Compounds Active: 3; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

11:	AID: 751	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent) [Primary Screening] Source: NMMLSC Compounds Active: 39; Tested: 23718 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

12:	AID: 2006	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	uHTS HTRF assay for identification of inhibitors of SUMOylation [Primary Screening] Source: Burnham Center for Chemical Genomics Protein Targets: SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi: 17390638]; Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi: 13111961] Compounds Active: 1042; Tested: 290927 Description: Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH... more

13:	AID: 2069	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	uHTS HTRF interference counterscreen assay for validation of inhibitors of SUMOylation [Primary Screening] Source: Burnham Center for Chemical Genomics Protein Targets: SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi: 17390638]; Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi: 13111961] Compounds Active: 207; Tested: 1233 Description: Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH... more

14:	AID: 1207	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Flow Cytometric GFP Protein Degradation Assay: Secondary Assay for disassembly of the 26S Proteasome [Primary Screening] Source: NMMLSC Compounds Active: 1; Tested: 3 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

15:	AID: 1062	Summary \| Data (Active)	Related BioAssays, Chemicals, Literature, Other Links
	Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent): Dose Response Assay [Confirmatory] Source: NMMLSC Compounds Active: 2; Tested: 21 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra, PhD Assay... more

16:	AID: 2011	Summary	Related BioAssays, Target, Literature, Other Links
	Summary assay for identification of inhibitors of SUMOylation [Summary] Source: Burnham Center for Chemical Genomics Protein Targets: SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi: 17390638]; Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi: 13111961] Substances Active: 0; Tested: 0 Description: Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH... more

17:	AID: 2018	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature, Other Links
	AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [Primary Screening] Source: Burnham Center for Chemical Genomics Protein Targets: SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi: 17390638]; Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi: 13111961] Compounds Active: 529; Tested: 1233 Description: Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH... more

18:	AID: 1824	Summary	Related BioAssays, Literature, Other Links
	Summary of Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent) [Summary] Source: NMMLSC Substances Active: 0; Tested: 0 Description: University of New Mexico Assay Overview: Assay Support: NIH 1 X01 MH077613-01 Assay for disassembly of the 26S Proteasome PI: Dorota Skowyra Assay... more

19:	AID: 1053	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature
	High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1 to follow up on purchased Analogs of Selected Hits from the screen. [Primary Screening] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 2; Tested: 161 Description: List of compounds to be tested: 184 purchased chemical analogs of selected hits identified in the in vitro PLK1-PBD binding primary screen AID 693, and... more

20:	AID: 693	Summary \| Data (Active)	Related BioAssays, Chemicals, Target, Literature
	High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1. [Primary Screening] Source: University of Pittsburgh Molecular Library Screening Center Protein Target: polo-like kinase [Homo sapiens] [gi: 21359873] Compounds Active: 127; Tested: 97041 Description: Extracted from the MH078944 proposal submitted by Dr. Michael Yaffe of MIT. The Polo-like kinases (Plks) play important roles in many cell cycle-related... more