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Items: 1 to 20 of 8840

1.

Agonist activity at ER alpha in human MCF7 cells assessed as PR gene expression after 24 hrs by laser scanning imaging cytometer analysis

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
3.

Suppression of ER alpha in human MCF7 cells after 24 hrs by immunostaining analysis

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
4.

Binding affinity to ER alpha (unknown origin) by LanthaScreen TR-FRET competitive binding assay

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
AID:
1205554
5.

Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor after 2 hrs by fluorescence polarization assay

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
6.
7.

Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor at 100000 nM after 2 hrs by fluorescence polarization assay

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
8.

Binding affinity to human ER-alpha

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
9.

Agonist activity at human ERalpha in human MCF7 cells assessed as progesterone receptor endogenous genes activation after 24 hrs by qPCR relative to estradiol

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
10.

Agonist activity at human ERalpha in human MCF7 cells assessed as progesterone receptor endogenous genes activation after 24 hrs by qPCR

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
AID:
1196506
11.
12.

Agonist activity at human ERalpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by ERE-luciferase reporter gene transfection assay

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
AID:
1196500
13.
14.

Displacement of [2,4,6,7-3H]17beta-estradiol from human recombinant ER-alpha after 18 hrs by liquid scintillation counting method relative to E2

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
15.

Binding affinity to estrogen receptor (unknown origin) incubated for 4 hrs

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
16.

Agonist activity at estrogen receptor (unknown origin) expressed in rat PC12 cells coexpressing ER-luc at 10 uM after 24 hrs

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
17.

Displacement of [3H]-E2 from recombinant human ERalpha at 20 uM after 9 hrs by competitive binding assay relative to control

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
18.
19.

Inhibition of ERalpha (unknown origin) transcriptional activity at 10 mM

Source:
ChEMBL
Protein Target:
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
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