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Results: 1 to 20 of 1790

12.

Agonist activity at human LXRbeta transfected in HEK293 cells at 0.1 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
13.

Agonist activity at human LXRbeta transfected in HEK293 cells at 1 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
14.

Agonist activity at LXRbeta (unknown origin) transfected in mouse SN4741 cells at 10 uM after 24 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
15.

Binding affinity to human LXRbeta-LBD by surface plasmon resonance [Confirmatory]

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
16.

Agonist activity at LXRbeta (unknown origin) expressed in CHOK1 cells assessed as induction of transactivation activity at 100 uM after 24 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
17.

Agonist activity at LXRbeta (unknown origin) expressed in CHOK1 cells assessed as induction of transactivation activity at 2 uM after 24 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
18.

Agonist activity at human LXRbeta-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
19.

Agonist activity at LXRbeta in human HepG2 cells assessed as LXRbeta transcription at 50 to 100 uM after 24 hrs by RT-qPCR analysis

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
20.

Binding affinity to LXRbeta (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor

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