Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 4597

1.

Inhibition of CYP2C9 in human liver microsomes [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
2.

Inhibition of recombinant CYP2C9 (unknown origin) by LC/MS/MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
3.

Time dependent inhibition of CYP2C9 in human liver microsomes assessed as shift at 10 uM

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
4.

Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS/competitive screening assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
5.

Inhibition of CYP2C9 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
6.

Inhibition of CYP2C9 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
7.

Inhibition of CYP2C9 (unknown origin) pre-incubated with enzyme [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
8.

Inhibition of CYP2C9 (unknown origin) co-incubated with enzyme [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
9.

Inhibition of CYP2C9 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
10.

Inhibition of CYP2C9 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
11.

Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide conversion to 4-hydroxy tolbutamide preincubated for 10 mins followed by NADPH addition measured after 15 mins by LC-MS/MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
12.

Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide conversion to 4-hydroxy tolbutamide at 0.25 uM preincubated for 10 mins followed by NADPH addition measured after 15 mins by LC-MS/MS analysis relative to control

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
13.

Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide conversion to 4-hydroxy tolbutamide at 2.5 uM preincubated for 10 mins followed by NADPH addition measured after 15 mins by LC-MS/MS analysis relative to control

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
14.

Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide conversion to 4-hydroxy tolbutamide at 25 uM preincubated for 10 mins followed by NADPH addition measured after 15 mins by LC-MS/MS analysis relative to control

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
15.

Inhibition of CYP2C9 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
16.

Inhibition of CYP2C9 in human liver microsomes after 2 to 45 mins by LC-MS/MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
17.

Inhibition of CYP2C9 (unknown origin) at 10 uM

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
18.

Inhibition of human CYP2C9 [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
19.

Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate after 15 mins by LC/MS/MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase
20.

Inhibition of CYP2C9 (unknown origin)

Source:
ChEMBL
Protein Target:
Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Refine your results

• What's this?

Actions on your results

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk