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Results: 1 to 20 of 1886

1.

Inhibition of HIF-1alpha in human MDA-MB-231 cells at 10 uM after 18 hrs by Western blotting analysis in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
2.

Inhibition of HIF-1 alpha in human MDA-MB-231 cells by Western blotting analysis in hypoxia condition [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
3.

Inhibition of HIF-1 alpha in human MDA-MB-468 cells by Western blotting analysis in hypoxia condition [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
4.

Inhibition of HIF-1 alpha in human PANC1 cells by Western blotting analysis in hypoxia condition [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
5.

Inhibition of HIF-1 alpha in human OVCAR3 cells by Western blotting analysis in hypoxia condition [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
6.

Inhibition of HIF-1 alpha in human PANC1 cells assessed as inhibition of Bcl2 expression at 1 to 20 uM by Western blotting analysis in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
7.

Inhibition of HIF-1 alpha in human OVCAR3 cells assessed as inhibition of Bcl2 expression at 1 to 20 uM by Western blotting analysis in normoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
8.

Inhibition of HIF-1 alpha in human PANC1 cells after 3 hrs by Western blotting analysis in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
9.

Inhibition of HIF-1 alpha in human PANC1 cells after 18 hrs by Western blotting analysis in hypoxia condition in presence of T40214

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
10.

Inhibition of HIF-1 alpha in human PC3 cells after 18 hrs by Western blotting analysis in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
11.

Inhibition of GST-tagged HIF-1 alpha (531 to 826) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of GST-tagged HIF-1 alpha/p300 interaction at 5 ug after overnight incubation by pull down assay in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
12.

Inhibition of HIF-1 alpha in human MDA-MB-468 cells assessed as proteasomal degradation at 4 to 7 uM after 18 hrs by immunoblotting analysis in hypoxia condition

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
13.

Inhibition of HIF-1 alpha in human MDA-MB-468 cells assessed as proteasomal degradation at 4 to 7 uM after 18 hrs by immunoblotting analysis in hypoxia condition in presence of MG132

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
14.

Inhibition of HIF-1 alpha in human MDA-MB-231 cells at 1 to 20 uM by Western blotting analysis

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
15.

Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
16.

Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc at 30 uM after 12 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
17.

Ratio of YC-1 IC50 to compound IC50 for hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
18.

Inhibition of HIF-1alpha-mediated VEGF secretion in human Hep3b cells by ELISA [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
19.

Inhibition of HIF-1alpha-mediated VEGF expression in human Hep3b cells by luciferase reporter gene assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
20.

Inhibition of HIF-1alpha in human LN229 cells under hypoxia condition by HRE-luciferase reporter gene assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8

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