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Items: 1 to 20 of 1319

1.

Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
2.

Inhibition of COX2-mediated PGD2 formation in LPS-stimulated human monocytes preincubated for 15 mins before arachidonic acid substrate addition measured after 30 mins by UPLC-MS/MS analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
3.

Inhibition of COX2-mediated PGF2alpha formation in LPS-stimulated human monocytes preincubated for 15 mins before arachidonic acid substrate addition measured after 30 mins by UPLC-MS/MS analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
4.

Inhibition of purified human COX-2 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid preincubated at 10 uM for 5 mins before substrate addition measured after 5 mins by HPLC analysis relative to control

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
5.

Inhibition of human recombinant COX2 using arachidonic acid as substrate

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
6.

Inhibition of human recombinant COX2 using arachidonic acid as substrate at 10 uM

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
7.

Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
8.

Inhibition of human COX-2 using arachidonic acid as substrate assessed as PGE2 formation after 2 mins by LC-MS/MS analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
9.

Inhibition of human recombinant COX-2 using arachidonic acid as substrate assessed as residual activity at 5 uM preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC analysis relative to control

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
10.

Inhibition of human recombinant COX-2 using arachidonic acid as substrate assessed as residual activity at 10 uM preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC analysis relative to control

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
11.

Inhibition of human recombinant COX2 assessed as residual activity preincubated at 5 uM for 5 mins by HPLC analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
12.

Inhibition of human recombinant COX2 preincubated for 5 mins by HPLC analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
13.

Inhibition of COX-2 (unknown origin)

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
14.

Inhibition of human recombinant COX2 after 2 mins by EIA

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
15.

Inhibition of human recombinant COX-2 expressed in insect cell system using arachidonic acid as substrate assessed as reduction of PGG2 to PGH2 incubated for 1 min prior to substrate addition measured after 25 secs by chromogenic assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
16.

Inhibition of human COX-2 using arachidonic acid at 10 uM after 5 mins by HPLC analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
17.

Inhibition of recombinant human COX2 using arachidonic acid as substrate up to 10 uM preincubated for 5 mins followed by substrate addition measured after 5 mins

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
18.

Inhibition of human COX-2 using arachidonic acid as substrate assessed as consumption of oxygen at 5 uM preincubated for 5 mins followed by substrate addition by oxygen electrode-based assay relative to control

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
19.

Inhibition of human recombinant COX-2 assessed as PGF2-alpha formation using arachidonic acid as substrate at 20 uM by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
20.

Inhibition of COX2 (unknown origin) by colorimetric method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
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