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Results: 1 to 20 of 10780

1.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in fatty acid uptake using [14C]-oleic acid pretreated for 24 hrs by liquid scintillation counting

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
2.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in insulin-stimulated glucose uptake using [1,2-3H]-2-deoxy-D-glucose treated 24 hrs before insulin challenge measured after 15 mins by liquid scintillation counting

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
3.

Agonist activity at in mouse C2C12 cells ERRalpha assessed as increase in PDK4 protein level after 24 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
4.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in ATP5b protein level after 24 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
5.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in MCAD mRNA level pretreated for 20 hrs by quantitative real-time PCR analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
6.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in PDK4 mRNA level pretreated for 20 hrs by quantitative real-time PCR analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
7.

Agonist activity at ERRalpha in mouse C2C12 cells assessed as increase in ATP5b mRNA level pretreated for 20 hrs by quantitative real-time PCR analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
9.

Inverse agonist activity at GAL4-fused ERRalpha (unknown origin) transfected in african green monkey CV1 cells at 1 uM after 24 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
10.

Ratio of kaempferol IC50 to compound IC50 for human GAL4-DBD-fused ERRalpha-LBD transcriptional activity

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
11.

Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of PDK4 mRNA expression at 2.5 to 10 uM after 48 hrs by RT-PCR analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
12.

Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of MCAD mRNA expression at 2.5 to 10 uM after 48 hrs by RT-PCR analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
13.

Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of PDK4 expression after 24 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
14.

Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of MCAD expression after 24 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
15.

Inverse agonist activity at GAL4-fused ERRalpha (unknown origin) transfected in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
16.

Inverse agonist activity at human GAL4-DBD-fused ERRalpha-LBD transfected in human HepG2 cells assessed as disruption of interaction with PGC-1alpha after 24 hrs by dual luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
17.

Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysis

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
18.

Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysis relative to 17beta-estradiol

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
19.

Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining method

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1
20.

Agonist activity at ERalpha receptor in human MCF7 cells assessed as stimulation of cell proliferation after 6 days by crystal violet staining method

Source:
ChEMBL
Protein Target:
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1

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