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Results: 1 to 20 of 21075

1.

Inhibition of mouse FPR1

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
2.

Antagonist activity at mouse FPR1 expressed in HEK293 cells assessed as inhibition of fMLFF-stimulated intracellular calcium mobilisation at 50 uM by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
3.
4.
5.

Agonist activity at FPR1 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization relative to fMLF

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
6.

Agonist activity at FPR1 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization [Confirmatory]

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
7.

Agonist activity at FPR1/FPR2 in human neutrophils assessed as induction of Ca2+ mobilization [Confirmatory]

Source:
ChEMBL
Protein Targets:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP; ...
Total:
2
8.

Agonist activity at FPR1/FPR2 in human neutrophils assessed as induction of Ca2+ mobilization relative to fMLF

Source:
ChEMBL
Protein Targets:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP; ...
Total:
2
9.

Activity at human FPR1 receptor at 10 uM

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
11.

Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisation at 30 uM after 1 hr by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
13.

Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation at 50 uM by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
15.

Antagonist activity at FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated calcium mobilization at 50 uM by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
16.

Reversible inhibition of FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated calcium mobilisation by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
17.

Antagonist activity at FPR1 in human neutrophils assessed as inhibition of PMA-stimulated neutrophil degranulation after 15 mins by fluorescence assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
19.

Agonist activity at FPR1 in human neutrophils assessed as increase in calcium mobilization at 50 uM by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
20.

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