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Results: 1 to 20 of 26859

1.

Binding constant for DLK kinase domain [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; Leucine-zipper protein kinase; ZPK; MAPK-upstream kinase; MUK; Mixed lineage kinase
2.

Kinase inhibition selectivity assay for compound SID-48409448

Source:
Burnham Center for Chemical Genomics
Protein Targets:
3-phosphoinositide-dependent protein kinase 1 isoform 1 [Homo sapiens]; ...
Total:
314
3.

Kinase Inhibitor Selectivity Profiling Assay

Source:
Ambit Biosciences
Protein Targets:
3-phosphoinositide-dependent protein kinase 1 isoform 1 [Homo sapiens]; ...
Total:
287
4.

Binding constant for LZK kinase domain [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 13; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK
5.

Inhibition of MLK2 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
6.
7.

Competitive binding affinity to MLK2 (unknown origin) at 10 uM in presence of ATP relative to control

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
8.

Inhibition of MLK2 (unknown origin) at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
9.

Binding constant for MLK2 kinase domain [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
10.

Binding constant for MLK2 kinase domain [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
11.

Inhibition of human MLK2 expressed in baculovirus insect cell system [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
12.

Inhibition of GST-MLK2 [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
13.

Inhibition of MLK3 in human monocytes assessed as inhibition of HIV1 Tat-induced TNFalpha release incubated for 30 mins prior to HIV1 Tat induction measured after 8 hrs

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
14.

Inhibition of MLK3 in human monocytes assessed as inhibition of HIV1 Tat-induced MCP-1 release incubated for 30 mins prior to HIV1 tat induction measured after 8 hrs

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
15.

Inhibition of MLK3 in human monocytes assessed as inhibition of HIV1 Tat-induced IL-6 release incubated for 30 mins prior to HIV1 Tat induction measured after 8 hrs

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
16.

Inhibition of MLK3 in human monocytes assessed as inhibition of HIV1 Tat-induced IL-8 release incubated for 30 mins prior to HIV1 Tat induction measured after 8 hrs

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
17.
18.
19.
20.

Inhibition of MLK3 in human monocytes assessed as inhibition of HIV1 Tat-induced IL-8 release at 300 nM incubated for 30 mins prior to HIV1 Tat induction measured after 8 hrs relative to Tat-treated control

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase

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