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Inhibition of CDK14/cyclinY (unknown origin) at 10 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of CDK14 (unknown origin) incubated for 6 hrs by NanoBRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of GST-tagged human recombinant full-length CDK14 (2 to end residues) expressed in baculovirus expression system preincubated for 30 mins by Lanthascreen Eu-Kinase binding assay
PFTAIRE2 DiscoveRx kinase panel
SummaryRelated BioAssays by Target
PFTK1 DiscoveRx kinase panel
CDK14/cyclinY(h) Kinase panel
Inhibition of CDK14/cyclin-Y (unknown origin) at 1 uM
Inhibition of CDK14/Cyclin Y (unknown origin) assessed as residual activity at 1 uM in presence of 33P-ATP incubated for 2 hrs by kinase selectivity assay
KinomeScan assay: inhibition of PFTK1
Assay data:108 Tested
KinomeScan assay: inhibition of PFTAIRE2
PFTAIRE1(CD14CGS1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
CDK14/cyclinY(h) Eurofins Kinase panel
CDK14/cyclinY(h) Millipore kinase panel
CDK14 (PFTK1)/CYC Invitrogen Lab (UK) kinase screen (BI)
Inhibition of human CDK14/cyclin-Y using RB protein as substrate incubated for 2 hrs by [gamma-33P]-ATP assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human PFTK1 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control
Inhibition of human PFTAIRE2 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control
Inhibition of DNA-tagged human PFTK1 assessed as percent of control at 50000 nM by qPCR analysis relative to control
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