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Results: 1 to 20 of 7738

1.

Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
4.

Binding affinity to PPAR-alpha (unknown origin) by fluorescence-based assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
5.

Inhibition of PPAR-alpha (unknown origin) by SPA assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
6.

Agonist activity at PPARalpha (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
7.
8.

Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
9.

Activation of PPARalpha in human HepG2 cells at 30 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
10.

Activation of PPARalpha in human HepG2 cells at 25 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
11.
13.

Inhibition of human PPARalpha at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
14.

Antagonist activity at human PPARalpha assessed as effect on TIPP-703-induced activity at 10 uM

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
15.

Transactivation of PPARalpha (unknown origin) relative to control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
16.

Agonist activity at PPARalpha LBD (unknown origin) transfected in human HepG2 cells co-expressing GAL4-DBD at 10 uM after 18 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
17.

Agonist activity at PPARalpha (unknown origin) transfected in HEK293 cells at 10 uM by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
18.

Agonist activity at PPARalpha (unknown origin) transfected in HEK293 cells at 100 nM by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
19.

Agonist activity at PPARalpha (unknown origin) transfected in HEK293 cells at 1 to 30 uM by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
20.

Agonist activity at PPARalpha (unknown origin)

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1

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