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Results: 1 to 20 of 8060

1.

Binding affinity to PPARalpha LBD (unknown origin) by surface plasmon resonance assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
2.

Agonist activity at PPARalpha LBD (unknown origin) assessed as induction of PGC1alpha co-activator activity by TR-FRET analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
3.
4.
5.
6.

Antagonist activity at GST-tagged PPAR-alpha (unknown origin) assessed as inhibition of GW7647-induced effect after 2 hrs by TR-FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
8.

Antagonist activity at human PPAR-alpha [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
9.

Agonist activity at human PPAR-alpha [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
10.

Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
13.

Binding affinity to PPAR-alpha (unknown origin) by fluorescence-based assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
14.

Inhibition of PPAR-alpha (unknown origin) by SPA assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
15.

Agonist activity at PPARalpha (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
16.
17.

Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
18.

Activation of PPARalpha in human HepG2 cells at 30 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
19.

Activation of PPARalpha in human HepG2 cells at 25 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1
20.

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