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Results: 1 to 20 of 1235

1.

Inhibition of COX1 (unknown origin)

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1114848
2.

Inhibition of cyclooxygenase-1 in Homo sapiens (human) whole blood assessed as TXB2 level at 10 uM by EIA

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1094731
3.

Inhibition of COX-1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
4.

Inhibition of cyclooxygenase-1 in Homo sapiens (human) whole blood assessed as thromboxane B2 production at 10 uM after 1 hr by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1093842
5.

Inhibition of cyclooxygenase-1 in Homo sapiens (human) whole blood assessed as thromboxane B2 production at 100 uM after 1 hr by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1093841
6.

Inhibition of COX-1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1093838
7.

Inhibition of COX1 (unknown origin) at 1 uM

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1086521
8.

Inhibition of COX1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
9.

Binding affinity to COX1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
10.

Binding affinity to COX1 (unknown origin)

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1084578
11.

Inhibition of COX-1 (unknown origin) at 10 uM

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1083358
12.

Inhibition of COX-1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
13.

Inhibition of human COX1 using arachidonic acid as substrate assessed as PGE2 formation incubated for 10 mins prior to substrate addition measured after 10 mins by ELISA [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
14.

Inhibition of human COX1 [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
AID:
1077201
15.

Inhibition of COX-1 in human whole blood assessed as thromboxane B2 level in serum after 5 mins by enzyme immunoassay [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
16.

Inhibition of COX1/COX2 (unknown origin) using arachidonic acid as substrate assessed as consumption of oxygen preincubated for 5 mins followed by substrate addition at 15 uM

Source:
ChEMBL
Protein Targets:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1; ...
Total:
2
17.

Inhibition of COX1 in human OVCAR3 cells using [14C]arachidonic acid as substrate preincubated for 30 mins before substrate addition by radioactivity scanning technique [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
18.

Inhibition of human platelet COX1 by whole blood assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
19.

Inhibition of COX1 (unknown origin) by EIA

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
20.

Inhibition of COX1 in human whole blood at 10 uM after 1 hr by ELISA

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

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