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Results: 1 to 20 of 2308

1.

Inhibition of wild type human CFTR chloride conductance expressed in forskolin-stimulated rat FRT cells at 100 nM by short-circuit current analysis in presence of transepithelial chloride gradient

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
2.

Inhibition of wild type human CFTR chloride conductance expressed in forskolin-stimulated rat FRT cells by short-circuit current analysis in presence of transepithelial chloride gradient [Confirmatory]

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
3.

Cystic fibrosis transmembrane conductance regulator positive modulator

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
4.

Cystic fibrosis transmembrane conductance regulator inhibitor

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
5.

Inhibition of CFTR in forskolin-stimulated human epithelial cells at 30 uM

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
9.

Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrophysiology assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
10.
17.

Summary assay for small molecule cystic fibrosis induced NFkb Inhibitors [Summary]

Source:
Burnham Center for Chemical Genomics
Protein Target:
cystic fibrosis transmembrane conductance regulator [Homo sapiens]
20.

Broad Institute Small-molecule targeting of CFTR: PDZ Trafficking Interactions Inhibitor Probe Project [Summary]

Source:
Broad Institute
Protein Targets:
Golgi-associated PDZ and coiled-coil motif-containing protein isoform b [Homo sapiens]; ...
Total:
2

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