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Results: 1 to 20 of 75

1.

Inhibition of human VAP1

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
2.

Stability of the compound assessed as human full length SSAO-mediated drug metabolism expressed in CHO cells measured as compound remaining after 20 mins

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
4.

Binding affinity to human recombinant VAP-1 by surface plasmon resonance analysis

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
5.

Activity at recombinant human VAP-1 assessed as hydrogen peroxide generation rate preincubated for 30 mins by Amplex Red assay

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
6.

Activity at recombinant human VAP-1 assessed as hydrogen peroxide generation rate per min/mg preincubated for 30 mins by Amplex Red assay relative to control

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
7.

Ratio of relative Vmax to Km for recombinant human VAP-1 assessed as hydrogen peroxide generation rate preincubated for 30 mins by Amplex Red assay relative to control

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
8.

Activity at recombinant human VAP-1 assessed as hydrogen peroxide generation rate per min/mg using benzylamine as substrate at 200 uM preincubated for 30 mins by Amplex Red assay relative to control

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
9.

Ratio of relative Vmax to Km for recombinant human VAP-1 assessed as hydrogen peroxide generation rate using benzylamine as substrate at 200 uM preincubated for 30 mins by Amplex Red assay

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
13.

Irreversible inhibition of human SSAO/VAP1 measuring H2O2 production after 24 hrs of dialysis by Resorufin/Amplex Red assay

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
14.

Inhibition of human SSAO/VAP1 measuring H2O2 production by Kitz and Wilson plot analysis

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
15.

Time dependent inhibition of human SSAO/VAP1 measuring H2O2 production by Resorufin/Amplex Red assay

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
16.

Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
17.

Inhibition of human recombinant VAP-1 expressed in CHO cells after 30 mins by coupled colorimetric method

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
18.

Inhibition of human recombinant VAP-1 expressed in CHO cells after 30 mins by coupled colorimetric method

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
19.

Binding affinity to human SSAO

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
20.

Activity of human SSAO measured as hydrogen peroxide production at 1 mM relative to benzylamine oxidation

Source:
ChEMBL
Protein Target:
Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1

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