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Results: 1 to 20 of 24807

1.

Inhibition of CCR6 (unknown origin) at 10 uM relative to control

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
2.

Antagonist activity at CCR6 (unknown origin)

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
3.

Binding affinity to CCR6 (unknown origin) at 10 uM by radioligand displacement assay

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
4.

Antagonist activity at CCR6 (unknown origin) assessed as inhibition of calcium flux at 10 uM

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
5.

Antagonist activity at CCR6 (unknown origin) assessed as inhibition of chemotaxis at 10 uM

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
12.
13.
15.

Binding affinity to human CCR6 receptor [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
16.

Inhibition of human CCR6 [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen=CD196
17.

Inhibition of CCR7 (unknown origin) at 10 uM relative to control

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD_antigen=CD197
18.

Antagonist activity at CCR7 in human CCRF-CEM cells assessed as inhibition of MIP-3beta-induced calcium flux at 5 uM preincubated for 15 mins by spectrophotometric analysis relative to control

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD_antigen=CD197
19.

Binding affinity to CCR7 (unknown origin) at 10 uM by radioligand displacement assay

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD_antigen=CD197
20.

Antagonist activity at CCR7 (unknown origin) assessed as inhibition of calcium flux at 10 uM

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD_antigen=CD197

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