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Results: 1 to 20 of 167

2.

Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
3.

Binding affinity to human recombinant FGF4 by surface plasmon resonance assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3
4.

Binding affinity to TAF1(2) (unknown origin) by thermal shift assay

Source:
ChEMBL
Protein Target:
Transcription initiation factor TFIID subunit 1; Cell cycle gene 1 protein; TBP-associated factor 250 kDa; p250; Transcription initiation factor TFIID 250 kDa subunit; TAF(II)250; TAFII-250; TAFII250
5.

Inhibition of Lonp1 in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay

Source:
ChEMBL
Protein Target:
Lon protease homolog, mitochondrial; Lon protease-like protein; LONP; Mitochondrial ATP-dependent protease Lon; Serine protease 15
9.

Inhibition of recombinant human PARP-7 at 10 uM relative to control

Source:
ChEMBL
Protein Target:
TCDD-inducible poly [ADP-ribose] polymerase; ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; Poly [ADP-ribose] polymerase 7; PARP-7
10.

Binding affinity to ATAD2 bromodomain (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis

Source:
ChEMBL
Protein Target:
ATPase family AAA domain-containing protein 2; AAA nuclear coregulator cancer-associated protein; ANCCA
11.

Binding affinity to TAF1 bromodomain-2 (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis

Source:
ChEMBL
Protein Target:
Transcription initiation factor TFIID subunit 1; Cell cycle gene 1 protein; TBP-associated factor 250 kDa; p250; Transcription initiation factor TFIID 250 kDa subunit; TAF(II)250; TAFII-250; TAFII250
12.

Inhibition of PI3Kgamma-mediated AKT Ser473 phosphorylation in ConA-induced BALB/C Mus musculus (mouse) lymph node cells after 24 hr by Western blot analysis

Source:
ChEMBL
Protein Target:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K
18.

Binding affinity to ATAD2 bromodomain (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis

Source:
ChEMBL
Protein Target:
ATPase family AAA domain-containing protein 2; AAA nuclear coregulator cancer-associated protein; ANCCA
19.

Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-mediated PKB/Akt phosphorylation preincubated for 30 mins followed by C5a stimulation measured after 5 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K
20.

Target deconvolution using SILAC Measured in Biochemical System- 2143-27_Activator_Dose_CherryPick_Activity

Source:
Broad Institute
Protein Targets:
Apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein; ...
Total:
6

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