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Activation of rat liver phosphofructokinase
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to PFKL in human NCI-H358 cells at 1 uM by mass spectrometry based pull down assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to PFKL in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay
Binding affinity to PFKM in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:1 Active, 1 Activity ≤ 1 µM, 224 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant rabbit muscle PFK expressed in PFK-deficient Escherichia coli DF1020DE3 using ATP/fructose 6 phosphate as substrate at 1 uM
Inhibition of rabbit muscle PFK at 500 uM
Inhibition of rabbit muscle PFK at 690 uM
Inhibition of rabbit muscle PFK at 94 uM
Inhibition of rabbit muscle PFK at 170 uM
Inhibition of phosphofructokinase AMP binding site
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