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Results: 1 to 20 of 590

1.

Inhibition of 6x-His-tagged TNKS1 (unknown origin) after 60 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
2.

Inhibition of human TNKS1 after 1 to 2 hrs by fluorescence polarization method [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
3.

Inhibition of human TNKS1 incubated for 30 mins prior to substrate addition measured after 2 hrs by HTRF method [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
4.

Inhibition of human 6xhis-tagged ARTD5 (1030 to 1317) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate at 10 uM by fluorescence assay relative to control

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
5.

Inhibition of human 6xhis-tagged ARTD5 (1030 to 1317) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate by fluorescence assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
6.

Inhibition of 6xhis-tagged ARTD5 (unknown origin) expressed in Escherichia coli BL21 Star (DE3) cells [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
7.

Inhibition of human 6xhis-tagged ARTD5 (1030 to 1317) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate at 0.5 to 10 uM by fluorescence assay

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
8.

Inhibition of recombinant 6XHis-tagged TNKS1 (1091 to 1325) (unknown origin) after 60 mins by spectrophotometric analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
9.

Inhibition of tankyrase1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
10.

Inhibition of human tankyrase1 after 30 mins by spectrophotometry [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
11.

Inhibition of human TNKS1 (1030 to 1317) using NAD+ as substrate by fluorescence assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
12.

Inhibition of tankyrase1/2 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Targets:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I; ...
Total:
2
13.

Inhibition of N-terminal GST-tagged human TNKS1 expressed in baculovirus infected sf21 cells after 60 mins by LC-MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
14.

Inhibition of TNSK1 (unknown origin) assessed as nicotinamide concentration by LC-MS analysis [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
15.

Inhibition of 6XHis-tagged tankyrase1 (1091 to 1325) (unknown origin) after 60 mins in presence of NAD [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
16.

Inhibition of TNKS1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
17.

Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
18.

Inhibition of TNSK1 (unknown origin) by NAD+-dependent autopoly(ADP ribosyl)lation assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
19.

Inhibition of N-terminal His6-tagged human TNKS1 (1091 to 1325 amino acid residues) after 60 mins by autoparsylation assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
20.

Binding affinity to human recombinant TNSK1 expressed in Escherichia coli by isothermal titration calorimetry [Confirmatory]

Source:
ChEMBL
Protein Target:
Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I

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