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Results: 1 to 20 of 1462

1.

Inhibition of Tel-fused ALK in mouse BA/F3 cells [Confirmatory]

Source:
ChEMBL
Protein Target:
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD_antigen=CD246
2.
3.
4.

Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB

Source:
Shanghai Institute of Organic Chemistry
Protein Targets:
Chain 1, E. Coli (Lacz) Beta-Galactosidase (R599a) In Complex With D- Galctopyranosyl-1-One; ...
Total:
3355
6.
7.
8.

Inhibition of NPM-ALK autophosphorylation in human SUDHL1 cells

Source:
ChEMBL
Protein Target:
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
9.

Inhibition of NPM-ALK autophosphorylation in human Karpas299 cells after 4 hrs

Source:
ChEMBL
Protein Target:
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
10.

Inhibition of NPM-ALK in human Karpas299 cells at 50 nM

Source:
ChEMBL
Protein Target:
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
11.
12.

Inhibition of wild type NPM/ALK kinase activity in BaF3 cells by radioenzymatic assay [Confirmatory]

Source:
ChEMBL
Protein Targets:
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD_antigen=CD246; ...
Total:
2
14.

Inhibition of wild type NPM/ALK autophosphorylation activity in BaF3 cells by antiphosphotyrosine immunoblotting assay [Confirmatory]

Source:
ChEMBL
Protein Targets:
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD_antigen=CD246; ...
Total:
2
15.

Inhibition of NPM-ALK [Confirmatory]

Source:
ChEMBL
Protein Targets:
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD_antigen=CD246; ...
Total:
2
16.

Antiproliferative activity against human NPM-ALK positive anaplastic large cell lymphoma karpas299 cell line [Confirmatory]

Source:
ChEMBL
Protein Targets:
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD_antigen=CD246; ...
Total:
2
17.

Inhibition of NPM-ALK autophosphorylation in mouse Ba/F3 NPM-ALK cells after 4 hrs

Source:
ChEMBL
Protein Target:
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
18.

Inhibition of NPM-ALK in mouse Ba/F3 NPM-ALK cells at 50 nM

Source:
ChEMBL
Protein Target:
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
19.

Inhibition of Tel-fused ROS in mouse BA/F3 cells [Confirmatory]

Source:
ChEMBL
Protein Target:
Proto-oncogene tyrosine-protein kinase ROS; Proto-oncogene c-Ros; Proto-oncogene c-Ros-1; Receptor tyrosine kinase c-ros oncogene 1; c-Ros receptor tyrosine kinase
20.

Inhibition of Tel-fused INSR in mouse BA/F3 cells [Confirmatory]

Source:
ChEMBL
Protein Target:
Insulin receptor; IR; CD_antigen=CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta

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