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Results: 1 to 20 of 961

2.

Antagonist activity at rat CCR5 assessed as inhibition of RANTES-induced calcium mobilization [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; MIP-1 alpha receptor; CD_antigen=CD195
3.

Antagonist activity at rabbit CCR5 assessed as inhibition of RANTES-induced calcium mobilization [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; MIP-1 alpha receptor; CD_antigen=CD195
5.

Antagonist activity at rat CCR2 [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; CD_antigen=CD192
6.

Binding affinity to rat CCR2 [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; CD_antigen=CD192
7.

Antagonist activity at CCR2 in rat spleen cells assessed as inhibition of CCL2-induced chemotaxis [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; CD_antigen=CD192
8.

Binding affinity to rat CCR2 [Confirmatory]

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; CD_antigen=CD192
9.

Inhibition of mouse CCR3 at 10 uM

Source:
ChEMBL
Protein Target:
Probable C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen=CD193
10.

Inhibition of mouse CCR3 [Confirmatory]

Source:
ChEMBL
Protein Target:
Probable C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen=CD193
11.

Antagonist activity at CCR3 receptor in mouse eosinophil assessed as as inhibition of chemotaxis [Confirmatory]

Source:
ChEMBL
Protein Target:
Probable C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen=CD193
12.

Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in BALB/c mouse eosinophils [Confirmatory]

Source:
ChEMBL
Protein Target:
Probable C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen=CD193
13.

Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Probable C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen=CD193
14.

Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxis at 1 uM

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CCR-4; CCR4; CD_antigen=CD194
16.

Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis at 1 uM by bioluminescent assay

Source:
ChEMBL
Protein Target:
C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CCR-4; CCR4; CD_antigen=CD194
18.

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