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Results: 1 to 20 of 3830

1.

Effect on 36chloride ion influx in mouse embryo cortical neurons in absence of GABA-A at 10 uM relative to basal value

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
2.

Effect on GABA-A-induced 36chloride ion influx in mouse embryo cortical neurons at 10 uM relative to basal value

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
3.

Increase in [3H]flunitrazepam binding to GABA-A receptor in mouse embryo cortical neurons

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
4.

Binding affinity to mouse brain GABA receptor [Confirmatory]

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
5.

Ratio of binding affinity for mouse brain Gamma-aminobutyric acid GABA-A receptor and housefly Gamma-aminobutyric acid receptor; NA denotes not available

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
6.

Ratio of binding affinity for mouse brain Gamma-aminobutyric acid receptor and housefly Gamma-aminobutyric acid receptor

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
7.

Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes after 30 min

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
8.

Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes in the presence of phenobarbital after 30 min

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
9.

Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes in the presence of Diazepam after 30 min

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
10.
11.
12.

In vivo percentage inhibition of flunitrazepam binding to mouse fore brain at 30 mg/kg

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
13.

Activation of chloride ion uptake into mouse brain synaptoneurosomes, no net uptake at 4 nM [Confirmatory]

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
14.

Activation of chloride ion uptake into mouse brain synaptoneurosomes [Confirmatory]

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
15.

Ex vivo inhibition of [3H]flunitrazepam binding to mouse GABA-A benzodiazepine receptor

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
16.

In vivo activity against GABA-A benzodiazepine receptor in mice

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
17.

In vivo activity against GABA-A benzodiazepine receptor in mice (No data)

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
18.

In vivo activity of compound was evaluated against benzodiazepine receptor in mice

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
19.

Agonistic activity against GABA-A receptor chloride uptake, super-agonist

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14
20.

Agonistic activity against GABA-A receptor chloride uptake, partial agonist

Source:
ChEMBL
Protein Targets:
Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; ...
Total:
14

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