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Results: 1 to 20 of 269

1.

Induction of alpha-glucosidase in human GM00372 cells using 4-methylumbelliferyl alpha-D-glucoside as substrate at 1.5 uM after 4 days by fluorescence spectrophotometry relative to untreated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
2.

Induction of alpha-glucosidase in human GM00372 cells using 4-methylumbelliferyl alpha-D-glucoside as substrate at 6.2 uM after 4 days by fluorescence spectrophotometry relative to untreated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
3.

Induction of alpha-glucosidase in human GM00372 cells using 4-methylumbelliferyl alpha-D-glucoside as substrate at <6.25 uM after 4 days by fluorescence spectrophotometry relative to untreated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
4.

Induction of alpha-glucosidase in human GM00372 cells using 4-methylumbelliferyl alpha-D-glucoside as substrate at 25 uM after 4 days by fluorescence spectrophotometry relative to untreated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
5.

Induction of alpha-glucosidase in human GM00372 cells using 4-methylumbelliferyl alpha-D-glucoside as substrate at 20 to 100 uM after 4 days by fluorescence spectrophotometry relative to untreated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
6.

Lysosomal alpha-glucosidase inhibitor

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
7.

Induction of acid alpha glucosidase activity in fibroblasts derived from patient relative to control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
8.

Inhibition of pure alpha-glucosidase (unknown origin) assessed as para-nitrophenol release at 420 nm OD [Confirmatory]

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
9.
10.

Inhibition of human recombinant GAA assessed as hydrolysis of bovine liver glycogen by Amplex red oxidase assay

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
11.

Increase in translocation of GAA to lysosomes in human wild type skin fibroblasts at 1 to 5 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
12.

Increase in translocation of GAA to lysosomes in human F2845 cells at 1 to 5 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
13.

Increase in translocation of GAA to lysosomes in human wild type fibroblasts at 15 uM after 6 days confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
14.

Increase in translocation of GAA to lysosomes in human wild type skin fibroblasts at 5 uM after 6 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
15.

Increase in translocation of GAA to lysosome in human F2845 cells at 5 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
16.

Increase in translocation of GAA to lysosome in human F0833 cells at 5 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
17.

Increase in translocation of GAA to lysosome in human F3248 cells at 5 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
18.

Increase in translocation of GAA to lysosome in human F2845 cells at 1 uM after 5 days by confocal laser-scanning microscopic analysis

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
19.

Increase in GAA activity in human wild type skin fibroblasts incubated for 5 days followed by 18 to 40 hrs wash out by fluorescence assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase
20.

Increase in GAA activity in human F2845 cells incubated for 5 days followed by 18 to 40 hrs wash out by fluorescence assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase

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