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Results: 1 to 20 of 401

1.

Activation of Nrf2 (unknown origin) expressed in CHO-ARE luc cells at 10 to 30 uM after 18 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
2.

Activation of Nrf2 (unknown origin) expressed in CHO-ARE luc cells at 10 uM after 18 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
3.

Activation of Nrf2 (unknown origin) expressed in CHO-ARE luc cells at 5.2 uM after 18 hrs by luciferase reporter gene assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
4.

Activation of Nrf2 (unknown origin) expressed in CHO-ARE-Luc cells after 18 hrs by luciferase reporter gene assay in presence of GSH

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
5.

Activation of Nrf2 in human VSMC assessed as induction of HO-1 expression at 3 uM after 18 hrs by immunoblotting analysis

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
6.

Activation of Nrf2 (unknown origin) expressed in CHO-ARE-Luc cells after 18 hrs by luciferase reporter gene assay

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
7.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 0.01 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
8.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 0.1 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
9.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 1 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
10.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 5 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
11.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 10 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
12.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells after 12 hrs by luciferase reporter gene assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
13.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 12.5 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
14.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 20 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
15.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 40 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
16.

Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells at 80 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
17.

Induction of Nrf2 nuclear translocation in human HCT116 cells at 10 uM by Western blot analysis

Source:
ChEMBL
Protein Target:
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
18.

Induction of Nrf2/Keap1 in human HCT116 cells assessed as induction of ARE activity at 50 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Targets:
Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2; Kelch-like protein 19; ...
Total:
2
19.

Induction of Nrf2/Keap1 in human HCT116 cells assessed as induction of ARE activity at 20 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Targets:
Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2; Kelch-like protein 19; ...
Total:
2
20.

Induction of Nrf2/Keap1 in human HCT116 cells assessed as induction of ARE activity at 80 uM after 12 hrs by luciferase reporter gene assay relative to control

Source:
ChEMBL
Protein Targets:
Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2; Kelch-like protein 19; ...
Total:
2

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