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Summary of probe development efforts to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): disc diffusion-based assay to identify compounds that inhibit Candida albicans growth
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Late stage results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): luminescence-based cell-based high throughput dose response assay to identify cytotoxic compounds using the 3T3 cell line
Assay data:1 Active, 11 Tested
Late stage results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): luminescence-based cell-based high throughput dose response assay to identify cytotoxic compounds using the HepG2 cell line
Assay data:11 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Late stage results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): Fluorescence polarization-based biochemical dose response assay for TPT1 inhibitors
Assay data:7 Active, 2 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage counterscreen results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical dose response assay to identify inhibitors of RNAse T1
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
Assay data:5 Active, 1 Activity ≤ 1 µM, 19 Tested
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
Assay data:11 Active, 3 Activity ≤ 1 µM, 19 Tested
Fluorescence polarization-based counterscreen assay for inhibitors of tRNA 2'-phosphotransferase (TPT1): biochemical high throughput screening assay to identify inhibitors of RNAse T1.
Assay data:1958 Active, 2372 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
Assay data:1765 Active, 2372 Tested
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
Assay data:2452 Active, 302755 Tested
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