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Fluorescence-based cell-based late stage dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) (MedChem Round 2)
Assay data:7 Active, 5 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage counterscreen for activators or inhibitors of TAAR1: Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to Jurkat human T lymphocyte cells
Assay data:4 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Fluorescence-based cell-based late stage dose response assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) (MDRUN002)
Assay data:3 Active, 3 Activity ≤ 1 µM, 8 Tested
Fluorescence-based cell-based late stage dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) (MDRUN002)
Assay data:4 Active, 4 Activity ≤ 1 µM, 8 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 agonists (MedChem Round 1)
Assay data:11 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 antagonists (MedChem Round 1)
Fluorescence-based cell-based late stage dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) (MedChem Round 1)
Assay data:4 Active, 4 Activity ≤ 1 µM, 11 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based late stage dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response (MedChem Round 1)
Assay data:1 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 antagonists
Assay data:32 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 agonists
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based late stage dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response.
Assay data:31 Active, 15 Activity ≤ 1 µM, 32 Tested
Fluorescence-based cell-based late stage dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1)
Assay data:32 Active, 30 Activity ≤ 1 µM, 32 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists
Assay data:2 Active, 415 Tested
Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1)
Assay data:376 Active, 99 Activity ≤ 1 µM, 415 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response.
Assay data:272 Active, 27 Activity ≤ 1 µM, 415 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists
Assay data:415 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective Ga16 antagonists
Assay data:940 Active, 2401 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify hTAAR1 agonists that also desensitize TAAR1 receptor response.
Assay data:1099 Active, 2401 Tested
Fluorescence-based cell-based primary high throughput confirmation assay to identify agonists of the human trace amine associated receptor 1 (TAAR1)
Assay data:1973 Active, 2401 Tested
Summary of the probe development effort to identify agonists of the human trace amine associated receptor 1 (TAAR1)
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