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Inhibition Assay from US Patent US9181187: "Therapeutic agent for urinary excretion disorder"
Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Prostanoid EP Receptor Binding Assay from Article 10.1016/j.bmc.2009.08.007: "Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists."
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mouse EP1 receptor (Prostanoid receptors)
Assay data:10 Active, 10 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Antagonist activity at mouse EP1 receptor expressed in CHOK1 cells assessed as inhibition of 17PTPGE2-induced calcium influx
Assay data:13 Active, 9 Activity ≤ 1 µM, 14 Tested
Antagonist activity at mouse EP1 receptor expressed in CHOK1 cells assessed as inhibition of 17PTPGE2-induced calcium influx at >100 uM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by scintillation counting
Assay data:16 Active, 3 Activity ≤ 1 µM, 29 Tested
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting
Assay data:5 Active, 1 Activity ≤ 1 µM, 22 Tested
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting
Assay data:3 Active, 1 Activity ≤ 1 µM, 16 Tested
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter
Assay data:5 Active, 27 Tested
Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation counting
Assay data:5 Active, 11 Tested
Assay data:3 Active, 11 Tested
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting
Assay data:4 Active, 23 Tested
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counter
Assay data:8 Active, 2 Activity ≤ 1 µM, 10 Tested
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation counting
Assay data:1 Active, 7 Tested
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cell membrane
Assay data:6 Tested
Assay data:4 Active, 19 Tested
Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1
Assay data:10 Active, 2 Activity ≤ 1 µM, 14 Tested
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