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Inhibition of Hec1-Nek2 protein-protein interaction in human K562 cells assessed as reduction in Nek2 level at 1 uM by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Hec1-Nek2 protein-protein interaction in human K562 cells at 100 nM measured after 6 hrs by coimmunoprecipitation assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as reduction in coimmunoprecipitated Hec1 level at 100 nM after 16 hrs by co-immunoprecipitation assay in presence of 500 nM proteasome inhibitor MG132
Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as induction of Nek2 degradation at 100 nM by western blot analysis in presence of 500 nM proteasome inhibition MG132
Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as induction of Nek2 degradation at 100 nM by western blot analysis
Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as reduction in Hec1 level at 100 nM by western blot analysis
Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation at 10 nM after 24 hrs by western blot analysis
Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation after 24 hrs by western blot analysis
Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as reduction in coimmunoprecipitated Hec1 level at 100 nM after 16 hrs by co-immunoprecipitation assay
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
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