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Results: 1 to 20 of 457

1.

Inhibition of ERK2 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2
2.

Inhibition of Insulin receptor (unknown origin) using biotinylated poly-Glu-Tyr (4:1) as substrate preincubated for 5 mins measured after 12 hrs [Confirmatory]

Source:
ChEMBL
Protein Target:
Insulin receptor; IR; CD_antigen=CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta
3.

Inhibition of C-terminal FLAG-tagged IKK beta (unknown origin) expressed in baculovirus system using IkappaBalpha as substrate after 40 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
4.

Inhibition of C-terminal FLAG-tagged JNK1 (unknown origin) expressed in baculovirus system using c-jun as substrate after 60 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1
5.

Inhibition of FLAG-tagged human recombinant IKKbeta phosphorylation expressed in baculovirus infected insect Sf9 cells after 1 hr by luminescence assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
6.

Inhibition of recombinant IKKbeta (unknown origin) using ulight-IkappaomegaBalpha as substrate after 2 hrs by LANCE ultra TR-FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
7.

Inhibition of mTOR (unknown origin) after 40 mins by TR-FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
8.

Inhibition of mTOR (unknown origin) by KINOMEscan assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
9.

Inhibition of IKKbeta (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
10.

Inhibition of mTOR (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
11.

Inhibition of human PKCzeta [Confirmatory]

Source:
ChEMBL
Protein Target:
Protein kinase C zeta type; nPKC-zeta
12.

Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
13.

Activation of PKCdelta (unknown origin) after 40 mins [Confirmatory]

Source:
ChEMBL
Protein Target:
Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta; Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit; Sphingosine-dependent protein kinase-1; SDK1
14.

Inhibition of JNK1 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1
15.

Inhibition of recombinant IKK2 (unknown origin) expressed in baculovirus expression system [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
17.

Inhibition of InsR (unknown origin) after 90 mins by TR-FRET/IMAP fluorescence polarization assay [Confirmatory]

Source:
ChEMBL
Protein Target:
Insulin receptor; IR; CD_antigen=CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta
18.

Inhibition of ERK2 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2
19.

Inhibition of IR (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Insulin receptor; IR; CD_antigen=CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta
20.

Inhibition of IKK2 (unknown origin) [Confirmatory]

Source:
ChEMBL
Protein Target:
Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB

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