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Articles about the ITGAL gene

LFA-1 and CD2 synergize for the Erk1/2 activation in the Natural Killer (NK) cell immunological synapse.
J Biol Chem. 2009 Aug 7; 284(32):21280-7. Epub 2009 Jun 4.

[J Biol Chem. 2009]
Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin.
Immunity. 2009 Mar 20; 30(3):384-96. Epub 2009 Mar 5.

[Immunity. 2009]
Increased monocyte alphaL, alphaM and beta2 integrin subunits in diabetes mellitus.
Clin Biochem. 2009 May; 42(7-8):634-40. Epub 2008 Dec 24.

[Clin Biochem. 2009]
» See all...

Reference sequences

RefSeq Alternative Splicing
See 2 reference mRNA sequence splice variants for the ITGAL gene.

Gene Information

More about the ITGAL gene
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain...

Also Known As: CD11A, LFA-1, LFA1A

Homologs

Homologs of the ITGAL gene
The ITGAL gene is conserved in chimpanzee, dog, cow, mouse, and rat.

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GenBank: DQ131904.1

Homo sapiens integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL) gene, complete cds