DNA Polymerase III

A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II.

Year introduced: 1991(1977)

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Tree Number(s): D08.811.913.696.445.308.300.235

MeSH Unique ID: D004258

Registry Number: EC 2.7.7.7

Entry Terms:

• Polymerase III, DNA
• DNA-Dependent DNA Polymerase III
• DNA Dependent DNA Polymerase III
• DNA Pol III
• DNA Polymerase delta
• Polymerase delta, DNA

Previous Indexing:

• DNA Nucleotidyltransferases (1968-1976)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Nucleotidyltransferases
DNA Nucleotidyltransferases
DNA-Directed DNA Polymerase
DNA Polymerase III