Myasthenia Gravis, Neonatal
A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Year introduced: 2000
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Subheadings:
Tree Number(s): C10.114.656.650, C10.668.758.725.650, C20.111.258.500.650
MeSH Unique ID: D020941
Entry Terms:
- Neonatal Myasthenia Gravis
- Antenatal Myasthenia Gravis
- Myasthenia Gravis, Antenatal
- Myasthenia Gravis, Neonatal, Persistent
- Myasthenia Gravis, Persistent, Neonatal
- Neonatal Myasthenia Gravis, Persistent
- Persistent Neonatal Myasthenia Gravis
- Myasthenia Gravis, Neonatal, Transient
- Myasthenia Gravis, Transient, Neonatal
- Neonatal Myasthenia Gravis, Transient
- Transient Neonatal Myasthenia Gravis
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