Meglutol

An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.

Year introduced: 1996

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Tree Number(s): D02.241.081.337.351.550

MeSH Unique ID: D015093

Registry Number: CLA99KCD53

Entry Terms:

• 3-Hydroxy-3-methylpentanedioic Acid
• 3 Hydroxy 3 methylpentanedioic Acid
• Acid, 3-Hydroxy-3-methylpentanedioic
• beta-Hydroxy-beta-Methylglutarate
• beta Hydroxy beta Methylglutarate
• 3-Hydroxy-3-methylglutaric Acid
• 3 Hydroxy 3 methylglutaric Acid
• Acid, 3-Hydroxy-3-methylglutaric

Previous Indexing:

• Anticholesteremic Agents (1966-1979)
• Antilipemic Agents (1966-1972)
• Glutarates (1966-1979)
• Hydroxy Acids (1975-1979)

Pharmacologic Action:

• Anticholesteremic Agents
• Hypolipidemic Agents
• Enzyme Inhibitors
• Hydroxymethylglutaryl-CoA Reductase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Carboxylic Acids
Acids, Acyclic
Dicarboxylic Acids
Glutarates
Meglutol