CADASIL
A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Year introduced: 2005
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Subheadings:
Tree Number(s): C10.228.140.300.150.477.200.100, C10.228.140.300.275.249, C10.228.140.300.400.203, C10.228.140.300.510.200.175, C10.228.140.300.775.200.200.100, C10.228.140.380.230.124, C14.907.253.092.477.200.100, C14.907.253.329.249, C14.907.253.560.200.175, C14.907.253.855.200.200.100, C16.320.129, C23.550.513.355.250.200.100, C23.550.717.489.250.200.100
MeSH Unique ID: D046589
Entry Terms:
- Dementia, Hereditary Multi-Infarct Type
- Dementia, Hereditary Multi Infarct Type
- Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
- Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
- CADASILM
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