Integrin alpha2beta1
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
Year introduced: 2003
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Subheadings:
Tree Number(s): D09.400.430.890.625.298, D12.776.395.550.625.298, D12.776.543.550.625.298, D12.776.543.750.685.200, D12.776.543.750.705.408.530.249, D12.776.543.750.705.408.850.199, D12.776.543.750.705.675.352, D12.776.543.750.705.876.280
MeSH Unique ID: D038982
Entry Terms:
- alpha2beta1, Integrin
- VLA-2
- VLA 2
- Glycoprotein Ia-IIa
- Glycoprotein Ia IIa
- alpha2beta1Integrin
- Very Late Antigen-2
- Late Antigen-2, Very
- Very Late Antigen 2
- CD49b-CD29
- CD49b CD29
- Platelet Membrane Glycoprotein Heterodimer Ia-IIa
- Platelet Membrane Glycoprotein Heterodimer Ia IIa
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