Saquinavir

An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.

Year introduced: 1997

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Subheadings:

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D03.633.100.531.770, D03.633.100.810.900

MeSH Unique ID: D019258

Registry Number: L3JE09KZ2F

Entry Terms:

• Saquinivir
• Saquinavir Monomethanesulfonate
• Monomethanesulfonate, Saquinavir
• Saquinavir Mesylate
• Ro 31-8959
• Ro 318959
• Ro 31 8959
• Invirase

Previous Indexing:

• HIV Protease/antagonists and inhibitors (1990-1992)
• Isoquinolines (1993-1996)
• Quinolines (1993-1996)

Pharmacologic Action:

• HIV Protease Inhibitors
• Cytochrome P-450 CYP3A Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Isoquinolines
Saquinavir

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Quinolines
Saquinavir