U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Primary Ovarian Insufficiency

Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.

Year introduced: 2011(1992)

PubMed search builder options

Subheadings:

Tree Number(s): C12.050.351.500.056.630.750, C12.100.250.056.630.750, C19.391.630.750

MeSH Unique ID: D016649

Entry Terms:

  • Ovarian Insufficiency, Primary
  • Premature Ovarian Failure
  • Ovarian Failure, Premature
  • Gonadotropin-Resistant Ovary Syndrome
  • Gonadotropin Resistant Ovary Syndrome
  • Resistant Ovary Syndrome
  • Fragile X-Associated Primary Ovarian Insufficiency
  • Fragile X Associated Primary Ovarian Insufficiency
  • Primary Ovarian Insufficiency, Fragile X-Associated
  • Primary Ovarian Insufficiency, Fragile X Associated
  • Fragile X Premature Ovarian Failure
  • Premature Ovarian Failure 1
  • FMR1-Related Primary Ovarian Insufficiency
  • FMR1 Related Primary Ovarian Insufficiency
  • Hypergonadotropic Ovarian Failure, X-Linked
  • Hypergonadotropic Ovarian Failure, X Linked
  • Premature Ovarian Failure, X-Linked
  • Premature Ovarian Failure, X Linked
  • X-Linked Hypergonadotropic Ovarian Failure
  • X Linked Hypergonadotropic Ovarian Failure

Previous Indexing:

See Also:

Supplemental Content

Loading ...