Hypomagnesemia primary [Supplementary Concept]

A progressive renal disorder characterized by excessive urinary Ca(2+) and Mg(2+) excretion. There is progressive loss of kidney function, and in about 50% of cases, the need for renal replacement therapy by the second decade of life. Germline mutations in the CLDN16 gene have been identified. OMIM: 603959

Date introduced: August 25, 2010

MeSH Unique ID: C537153

Heading Mapped to:

• Nephrocalcinosis
• Renal Tubular Transport, Inborn Errors
• Hypercalciuria

Entry Terms:

• Magnesium, defect in renal tubular transport of
• Hypomagnesemia, isolated renal
• Hypomagnesemia, familial, with hypercalciuria and nephrocalcinosis
• Hypomagnesemia 3, Renal
• Hypomagnesemia, Primary, Due To Defect In Renal Tubular Transport Of Magnesium