saracatinib [Supplementary Concept]

inhibits c-Src and Abl kinases

Date introduced: December 3, 2006

MeSH Unique ID: C515233

Registry Number: 9KD24QGH76

Heading Mapped to:

• Quinazolines
• Benzodioxoles

Entry Terms:

• N-(5-chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
• 4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methyl-1- piperazinyl)ethoxy)-5-((tetrahydro-2H-pyran-4-yl)oxy)-
• AZD 0530
• AZD-0530
• AZD0530
• saracatinib difumerate
• AZD0530 Difumarate
• N-(5-chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-((tetrahydro- 2H-pyran-4-yl)oxy)quinazolin-4-amine bi((2E)-but-2-enedioate)

Pharmacologic Action:

• Antineoplastic Agents
• Enzyme Inhibitors